Busin M, Brauweiler P, Böker T, Spitznas M
University Eye Hospital, Bonn, Federal Republic of Germany.
Ophthalmology. 1990 Apr;97(4):401-5; discussion 405-6. doi: 10.1016/s0161-6420(90)32570-8.
In a retrospective study, the authors analyzed visual results and postoperative complications in a series of 14 consecutive patients who had undergone penetrating keratoplasty and implantation of a posterior chamber intraocular lens (PC IOL) in the absence of the posterior capsule. Seven patients suffered from aphakic bullous keratopathy and seven from pseudophakic bullous keratopathy. Postoperative follow-up was 7.6 months on the average. Best-corrected postoperative visual acuity was 20/60 or better in four cases and 20/200 or better in eight. Glaucoma was present before surgery in four eyes, which persisted in all cases and developed in four new cases. Results of gonioscopic examination showed the postoperative development of goniosynechiae in four eyes. Pseudophakodonesis of various extent was present in ten eyes. Preoperatively, cystoid macular edema was diagnosed angiographically in one case. It did not improve after surgery and was seen in three additional eyes postoperatively. Causes for postoperative visual acuity lower than 20/200 were cystoid macular edema in three cases, graft rejection in one case, central retinal scar in one case, and optic nerve atrophy in one case. A distortion of the pupil was seen in three eyes in miosis and in four additional eyes in mydriasis. Corneal thickness as well as anterior chamber depth were within normal limits. Fluorophotometric evaluation of the blood-aqueous barrier showed values comparable with those obtained after intracapsular cataract extraction and implantation of an iris-fixated IOL. Despite the relatively good visual results, the high postoperative incidence of cystoid macular edema and/or glaucoma may discourage the use of this technique.
在一项回顾性研究中,作者分析了连续14例在无后囊情况下接受穿透性角膜移植术及后房型人工晶状体(PC IOL)植入术患者的视力结果和术后并发症。7例患者患有无晶状体大泡性角膜病变,7例患有假晶状体大泡性角膜病变。术后平均随访7.6个月。术后最佳矫正视力4例为20/60或更好,8例为20/200或更好。4只眼术前存在青光眼,所有病例中青光眼均持续存在,且有4例新发病例。前房角镜检查结果显示4只眼术后发生了前房角粘连。10只眼存在不同程度的人工晶状体震颤。术前,1例经血管造影诊断为黄斑囊样水肿。术后未改善,且术后在另外3只眼中也出现了黄斑囊样水肿。术后视力低于20/200的原因包括3例黄斑囊样水肿、1例移植排斥反应、1例视网膜中央瘢痕和1例视神经萎缩。3只眼在瞳孔缩小时出现瞳孔变形,另外4只眼在瞳孔散大时出现瞳孔变形。角膜厚度及前房深度均在正常范围内。血-房水屏障的荧光光度评估显示其值与囊内白内障摘除术及虹膜固定人工晶状体植入术后所获得的值相当。尽管视力结果相对较好,但术后黄斑囊样水肿和/或青光眼的高发生率可能会阻碍该技术的应用。