Department of Ophthalmology, Charité, University Medicine Berlin, Augustenburger Platz 1, 13353, Berlin, Germany,
Graefes Arch Clin Exp Ophthalmol. 2013 Apr;251(4):1151-6. doi: 10.1007/s00417-012-2226-y. Epub 2012 Dec 19.
To evaluate the indication, visual outcome, and complication rate after implantation of a posterior iris-claw aphakic intraocular lens (IOL) during penetrating keratoplasty.
This retrospective study comprised 23 eyes (23 patients) without adequate capsule support undergoing posterior iris-claw aphakic IOL implantation (Verisyse/Artisan) during penetrating keratoplasty between 2005 and 2010. Mean follow-up was 18 months (range from 12 to 37 months).
The IOLs were inserted during an IOL exchange in 17 eyes and as a secondary procedure in six aphakic eyes. Pseudophakic bullous keratopathy with corneal scar after anterior chamber intraocular lens (ACIOL) was the main indication for penetrating keratoplasty in 16 eyes (69.6 %). The final corrected distance visual acuity (CDVA) in logMAR (mean 1.0 ± 0.46) improved significantly (p < 0.05) compared to the preoperative CDVA (mean 1.8 ± 0.73). Twenty eyes (86.9 %) had a final visual acuity in logMAR better than the pre-operative CDVA. The mean postoperative IOP 16.3 mmHg ± 4.0 was not significantly (p > 0.05) higher compared to the preoperative IOP 15.6 mmHg ± 5.1. Complications included slight temporary pupil ovalization in three eyes (13.0 %) and iris-claw IOL sublocation in three eyes (13.0 %); all IOLs could be easily repositioned. Cystoid macular edema occured in one eye (4.3 %) 8 weeks after primary surgery. All grafts remained clear without any sign of graft rejection.
Retropupillar iris-claw IOL during penetrating keratoplasty provides good visual outcomes with a favorable complication rate, and can be used for a wide range of indications in eyes without adequate capsule support.
评估穿透性角膜移植术中后房型虹膜夹型无晶状体眼人工晶状体(IOL)植入的适应证、视力结果和并发症发生率。
本回顾性研究包括 2005 年至 2010 年间 23 只眼(23 例患者)因缺乏囊袋支持而接受后房型虹膜夹型无晶状体眼 IOL(Verisyse/Artisan)植入的患者。平均随访时间为 18 个月(12 至 37 个月)。
17 只眼行 IOL 置换时植入 IOL,6 只眼无晶状体眼行二期手术植入。16 只眼(69.6%)穿透性角膜移植术的主要适应证是前房人工晶状体(ACIOL)后发性白内障伴角膜瘢痕。最终 logMAR 最佳矫正视力(BCVA)(均值 1.0 ± 0.46)较术前 logMAR 最佳矫正视力(均值 1.8 ± 0.73)显著提高(p<0.05)。20 只眼(86.9%)的最终视力优于术前 logMAR 最佳矫正视力。术后平均眼压 16.3mmHg ± 4.0,与术前眼压 15.6mmHg ± 5.1 相比差异无统计学意义(p>0.05)。3 只眼(13.0%)出现轻微短暂性瞳孔椭圆形,3 只眼(13.0%)出现虹膜夹 IOL 下移位,所有 IOL 均能轻松复位。1 只眼(4.3%)在初次手术后 8 周发生黄斑囊样水肿。所有移植物均保持透明,无移植物排斥迹象。
穿透性角膜移植术中后房型虹膜夹型 IOL 提供了良好的视力结果,并发症发生率低,可用于无囊袋支持的多种适应证的眼。