Centre of Microbial and Plant Genetics, K.U. Leuven, Kasteelpark Arenberg 20, P.O. Box 2460, 3001 Leuven, Belgium.
Benef Microbes. 2010 Nov;1(4):335-42. doi: 10.3920/BM2010.0032.
Probiotic bacteria are administered as live micro-organisms to provide a health benefit to the host. Knowledge on adaptation factors that promote the survival and persistence of probiotics in the intestine is key to understand and improve their ecological and probiotic performance. Adaptation factors include adhesins, molecules conferring stress tolerance and nutritional versatility, antimicrobial products against competing microbes, and factors promoting resistance against the host immune system. Here, we present an overview of the current knowledge on adaptation factors of probiotic lactobacilli, with focus on the prototypical and widely documented probiotic strain Lactobacillus rhamnosus GG.
益生菌是被当作活的微生物来使用的，以给宿主带来健康益处。了解促进益生菌在肠道中存活和持续存在的适应因子是理解和改善其生态和益生菌性能的关键。适应因子包括黏附素、赋予耐受力和营养多样性的分子、针对竞争微生物的抗菌产品以及促进抵抗宿主免疫系统的因素。在这里，我们概述了益生菌乳杆菌适应因子的现有知识，重点介绍了原型和广泛记录的益生菌菌株鼠李糖乳杆菌 GG。
