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胸段食管穿孔的治疗:16例分析

Management of intrathoracic oesophageal perforation: analysis of 16 cases.

作者信息

Tettey M, Edwin F, Aniteye E, Sereboe L, Tamatey M, Entsua-Mensah K, Kotei D, Frimpong-Boateng K

机构信息

National Cardiothoracic Centre, Korle Bu Teaching Hospital, Korle Bu, Accra, Ghana.

出版信息

Trop Doct. 2011 Oct;41(4):201-3. doi: 10.1258/td.2011.110120. Epub 2011 Aug 10.

Abstract

Intrathoracic oesophageal perforation remains a life-threatening lesion that requires early diagnosis and the appropriate intervention in order to reduce morbidity and mortality. Management depends largely on the cause of the perforation, the integrity of the oesophagus and the time lapse between the perforation and the commencement of treatment. Our aim was to evaluate the management options that were employed in the treatment of patients with oesophageal perforation and the outcome. The records of 16 patients (11 males and 5 females) who had been operated on from 1994-2009 were retrospectively reviewed. Their ages ranged between 2-66 years (mean 36.4). Malignant oesophageal perforations were excluded from the study. The aetiology was iatrogenic in 10 (62.5%), foreign bodies five (31.2%) and spontaneous one (6.2%). Six patients (37.5%) presented within 24 h of their injury and 10 (62.5%) presented after 24 h. Thoracotomy and intrathoracic primary repair was possible in five (31.2%) cases. Oesophagectomy, cervical oesophagostomy and feeding gastrostomy were carried out in 11 (68.8%). Oesophageal substitution was by colon, routed retrosternally. One patient (6.2%) died after oesophagectomy from overwhelming sepsis. Oesophageal perforation is a life-threatening condition. Early diagnosis and the institution of prompt and appropriate treatment ensure good outcome.

摘要

胸段食管穿孔仍然是一种危及生命的病变,需要早期诊断并进行适当干预,以降低发病率和死亡率。治疗方法很大程度上取决于穿孔的原因、食管的完整性以及穿孔与治疗开始之间的时间间隔。我们的目的是评估用于治疗食管穿孔患者的治疗选择及其结果。对1994年至2009年期间接受手术的16例患者(11例男性和5例女性)的记录进行了回顾性研究。他们的年龄在2岁至66岁之间(平均36.4岁)。本研究排除恶性食管穿孔。病因是医源性的有10例(62.5%),异物所致5例(31.2%),自发性1例(6.2%)。6例患者(37.5%)在受伤后24小时内就诊,10例(62.5%)在24小时后就诊。5例(31.2%)患者可行开胸手术并进行胸内一期修复。11例(68.8%)患者进行了食管切除术、颈部食管造口术和胃造瘘术。食管替代采用结肠,经胸骨后途径。1例患者(6.2%)在食管切除术后死于严重败血症。食管穿孔是一种危及生命的疾病。早期诊断并及时采取适当治疗可确保良好的预后。

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