Departments of Pharmacy and Critical Care, Sheffield Teaching Hospitals NHS Foundation Trust, Northern General Hospital, Herries Road, Sheffield, S5 7AU, UK.
Int J Clin Pharm. 2011 Oct;33(5):755-8. doi: 10.1007/s11096-011-9538-6. Epub 2011 Jul 22.
To identify the input of specialist critical care pharmacists into patient care, promoting safe and effective medication therapy by quantifying medicines related interventions on a Neurocritical Care Unit. Setting UK 19-bedded Neurocritical Care Unit providing a tertiary referral service for Neurosurgical and Neurology patients.
Prospective observational study of clinical pharmacist interventions conducted over a 2 week period in July 2010. Interventions were recorded, categorised and independently assessed by a panel of 5 healthcare professionals for potential patient harm if the intervention had not been made.
Quantity and potential severity of clinical pharmacist interventions recorded.
246 interventions were made in 55 patients over the 10 day observational period. A median of 7.0 (1.5; 12.0) and 2.0 (1.0; 4.0) interventions were made in Level 3 and 2 patients respectively. Mean potential severity of patient harm per intervention was 3.7 (1.12); range 0.8-7.0. Central Nervous System medicines comprised the most common therapeutic group affected (37.8%). Medication errors accounted for 87 of the 246 interventions (35.4%).
The results of the clinical pharmacist intervention evaluation demonstrated an important role for critical care pharmacists in the safe and effective use of medicines in a UK Neurocritical care unit.
通过量化神经重症监护病房的药物相关干预措施，确定专科重症监护药剂师对患者护理的投入，以促进安全有效的药物治疗。
英国设有 19 张病床的神经重症监护病房，为神经外科和神经内科患者提供三级转诊服务。
对临床药师干预措施进行了为期 2 周的前瞻性观察研究，时间为 2010 年 7 月。干预措施由 5 名医疗保健专业人员组成的小组进行记录、分类和独立评估，如果没有进行干预，评估其是否可能对患者造成伤害。
记录临床药师干预措施的数量和潜在严重程度。
在 10 天的观察期内，对 55 名患者进行了 246 次干预。3 级和 2 级患者的中位数分别为 7.0（1.5；12.0）和 2.0（1.0；4.0）。每个干预措施潜在的严重程度平均为 3.7（1.12）；范围为 0.8-7.0。中枢神经系统药物是受影响最常见的治疗药物组（37.8%）。药物错误占 246 次干预中的 87 次（35.4%）。
临床药师干预评估的结果表明，在英国神经重症监护病房，重症监护药剂师在安全有效地使用药物方面发挥着重要作用。
