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神经重症监护药学的发展:历史视角与未来展望

The Evolution of Neurocritical Care Pharmacy: Historical Perspectives and Future Horizons.

作者信息

Rhoney Denise H, Cook Aaron M, Berger Karen, Mahmoud Sherif Hanafy, Brophy Gretchen M, Farrokh Salia, Human Theresa, Lewin John, Mucksavage Jeffrey J, Sangha Kiranpal S, Tesoro Eljim P

机构信息

Division of Practice Advancement and Clinical Education, UNC Eshelman School of Pharmacy, 325 Beard Hall, Campus Box 7574, Chapel Hill, NC, 27599-7574, USA.

Department of Pharmacy Practice and Science, University of Kentucky College of Pharmacy, Lexington, KY, USA.

出版信息

Neurocrit Care. 2025 Mar 25. doi: 10.1007/s12028-025-02239-8.

DOI:10.1007/s12028-025-02239-8
PMID:40133755
Abstract

This article reviews the history and evolution of the neurocritical care (NCC) pharmacy, a subspecialty of critical care pharmacy that focuses on the care of patients with acute neurological disorders. The origins of NCC pharmacies in the 1960s and 1970s are described, when pharmacists began to participate in patient rounds, clinical pharmacokinetic consults, and translational research with neurosurgeons and neurologists. The article also discusses the current state of NCC pharmacy practice, research, and education, highlighting the role of pharmacists as essential members of the NCC team, the contributions of pharmacists to NCC research and guidelines, and the challenges and opportunities for education and training in this unique subspecialty. Finally, the article envisions the future of NCC pharmacy, emphasizing the need for high expectations, visionary leadership, innovative education models, a robust scientific foundation, and multidisciplinary collaboration to advance NCC pharmacy and improve patient outcomes.

摘要

本文回顾了神经重症监护(NCC)药学的历史与发展,它是重症监护药学的一个子专业,专注于急性神经系统疾病患者的护理。文中描述了20世纪60年代和70年代NCC药房的起源,当时药剂师开始参与患者查房、临床药代动力学咨询以及与神经外科医生和神经科医生的转化研究。本文还讨论了NCC药学实践、研究和教育的现状,强调了药剂师作为NCC团队重要成员的作用、药剂师对NCC研究和指南的贡献,以及在这个独特子专业中教育和培训所面临的挑战与机遇。最后,本文展望了NCC药学的未来,强调需要有高期望、有远见的领导力、创新的教育模式、坚实的科学基础以及多学科合作,以推动NCC药学发展并改善患者预后。

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本文引用的文献

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Evaluating the Need for Competency-Based Pharmacy Education (CBPE): The Report of the 2023-2024 Academic Affairs Standing Committee.评估以能力为基础的药学教育(CBPE)的需求:2023-2024 学年学术事务常务委员会的报告。
Am J Pharm Educ. 2024 Aug;88(8):100728. doi: 10.1016/j.ajpe.2024.100728. Epub 2024 Jun 6.
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The Need for Competency-Based Education.需要基于能力的教育。
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Guidelines for Seizure Prophylaxis in Adults Hospitalized with Moderate-Severe Traumatic Brain Injury: A Clinical Practice Guideline for Health Care Professionals from the Neurocritical Care Society.
成人中-重度创伤性脑损伤住院患者癫痫预防指南:神经重症监护学会卫生保健专业人员临床实践指南。
Neurocrit Care. 2024 Jun;40(3):819-844. doi: 10.1007/s12028-023-01907-x. Epub 2024 Feb 5.
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Competency-based pharmacy education definition: What components need to be defined to implement it?基于能力的药学教育定义:实施它需要定义哪些组成部分?
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The AACP Academic Affairs Committee's Final 2022 Curricular Outcomes and Entrustable Professional Activities (COEPA) for Pharmacy Graduates to Replace 2013 CAPE and 2016 EPAs.美国药学院协会学术事务委员会 2022 年课程学习成果和药学毕业生可信赖专业活动(COEPA)终版,用以替代 2013 年药学教育认证委员会标准和 2016 年毕业后医药教育项目标准。
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Multicenter comparison of antiplatelet treatment strategies for urgent/emergent neuroendovascular stenting.紧急/急诊神经血管内支架置入抗血小板治疗策略的多中心比较
Interv Neuroradiol. 2023 Jul 4:15910199231180003. doi: 10.1177/15910199231180003.
7
Comparison of nimodipine formulations and administration techniques via enteral feeding tubes in patients with aneurysmal subarachnoid hemorrhage: A multicenter retrospective cohort study.尼莫地平制剂经肠内喂养管给药技术在动脉瘤性蛛网膜下腔出血患者中的比较:一项多中心回顾性队列研究。
Pharmacotherapy. 2023 Apr;43(4):279-290. doi: 10.1002/phar.2791. Epub 2023 Mar 16.
8
The Future of Critical Care: Optimizing Technologies and a Learning Healthcare System to Potentiate a More Humanistic Approach to Critical Care.重症监护的未来:优化技术与建立学习型医疗体系,以强化更具人文关怀的重症监护方法。
Crit Care Explor. 2022 Mar 15;4(3):e0659. doi: 10.1097/CCE.0000000000000659. eCollection 2022 Mar.
9
Optimization of critical care pharmacy clinical services: A gap analysis approach.重症监护药房临床服务的优化:一种差距分析方法。
Am J Health Syst Pharm. 2021 Nov 9;78(22):2077-2085. doi: 10.1093/ajhp/zxab237.
10
PHarmacist Avoidance or Reductions in Medical Costs in Patients Presenting the EMergency Department: PHARM-EM Study.急诊科患者中药剂师避免或降低医疗费用:药剂师 - 急诊科研究
Crit Care Explor. 2021 Apr 26;3(4):e0406. doi: 10.1097/CCE.0000000000000406. eCollection 2021 Apr.