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新生儿血小板减少症的诊断与治疗。

Diagnosis and management of neonatal thrombocytopenia.

机构信息

Department of Paediatric Oncology and Haematology, Charité - University of Berlin, Berlin, Germany.

出版信息

Semin Fetal Neonatal Med. 2011 Dec;16(6):305-10. doi: 10.1016/j.siny.2011.07.008. Epub 2011 Aug 10.

DOI:10.1016/j.siny.2011.07.008
PMID:21835709
Abstract

Thrombocytopenia is the most common haematological abnormality in newborns admitted to neonatal care units and serves as an important indicator of underlying pathological processes of mother or child. In most cases thrombocytopenia is mild to moderate and resolves within the first weeks of life without any intervention. However, in some neonates thrombocytopenia is severe or may reflect an inborn platelet disorder. As clinical course and outcome of thrombocytopenia depend on the aetiology of thrombocytopenia, an appropriate work-up is essential to guide therapy in neonates with thrombocytopenia and to avoid severe bleeding.

摘要

血小板减少症是新生儿入住新生儿重症监护病房时最常见的血液学异常,也是母亲或儿童潜在病理过程的重要指标。大多数情况下,血小板减少症为轻度至中度,在生命的头几周内无需任何干预即可自行缓解。然而,在一些新生儿中,血小板减少症可能较为严重,或反映了先天性血小板疾病。由于血小板减少症的临床病程和结局取决于血小板减少症的病因,因此对血小板减少症新生儿进行适当的检查对于指导治疗和避免严重出血至关重要。

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Diagnosis and management of neonatal thrombocytopenia.新生儿血小板减少症的诊断与治疗。
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Cureus. 2023 Dec 14;15(12):e50503. doi: 10.7759/cureus.50503. eCollection 2023 Dec.
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Romiplostim use in pregnant women with immune thrombocytopenia.罗米司亭在免疫性血小板减少症孕妇中的应用。
Am J Hematol. 2023 Jan;98(1):31-40. doi: 10.1002/ajh.26743. Epub 2022 Oct 10.
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Refractory thrombocytopenia could be a rare initial presentation of Noonan syndrome in newborn infants: a case report and literature review.
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BMC Pediatr. 2022 Mar 17;22(1):142. doi: 10.1186/s12887-021-02909-4.
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Risk factors for severity of thrombocytopenia in full term infants: a single center study.足月新生儿血小板减少症严重程度的危险因素:一项单中心研究。
Ital J Pediatr. 2021 Jan 12;47(1):7. doi: 10.1186/s13052-021-00965-1.
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Thrombocytopenia and Associated Factors in Neonates Admitted to NICU during Years 2010_2011.2010 - 2011年入住新生儿重症监护病房的新生儿血小板减少症及其相关因素
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