Kim Hyun-Soo, Jee Won-Hee, Ryu Kyung-Nam, Cho Kil-Ho, Suh Jin-Suck, Cho Jae-Hyun, Choi Yun-Sun, Lee Sung Moon, Lee Jong-Min, Sung Mi Sook, Kim Jee Young, Jung Eun Sun, Chung Yang-Guk, Ok In-Young
Department of Radiology, Seoul St Mary's Hospital, School of Medicine, The Catholic University of Korea, Korea.
Acta Radiol. 2011 Oct 1;52(8):875-80. doi: 10.1258/ar.2011.110180. Epub 2011 Aug 11.
Chondromyxoid fibroma is a rare benign primary bone tumor of cartilage. Despite a characteristic radiographic appearance, chondromyxoid fibroma with atypical radiographic findings may mimic more common tumors.
To describe the MR findings of chondromyxoid fibroma.
MR images of 19 histopathologically confirmed chondromyxoid fibromas were retrospectively analyzed for signal intensity, periosteal reaction, adjacent abnormal bone marrow and soft tissue signal, and patterns of contrast enhancement.
All cases of chondromyxoid fibroma showed hypointense to intermediate signal intensity and internal hyperintense foci were observed in seven (37%) cases on T1-weighted images. On T2-weighted images, all lesions were hyperintense: peripheral intermediate signal band with central hyperintense signal in 11 (58%) of 19 lesions, whereas diffusely hyperintense with heterogeneous pattern in eight (42%). Periosteal reaction was observed in 11 (58%) of 19 cases. Adjacent abnormal bone marrow or soft tissue signal was observed in 12 (63%) or 14 (74%) of 19 cases, respectively. On contrast-enhanced T1-weighted images, peripheral nodular enhancement was observed in 69% (11/16) and diffuse contrast enhancement was observed in 31% (5/16) with homogeneous (n = 3) or heterogeneous (n = 2) patterns. Among the cases with peripheral nodular enhancement, the peripheral nodular enhancing portion generally corresponded to the peripheral intermediate signal band on T2-weighted images, although the peripheral enhancement was not as wide as a band of intermediate signal intensity. On the other hand, the central non-enhancing portion generally corresponded to the central hyperintense signal intensity on T2-weighted images.
The helpful features of chondromyxoid fibroma are the peripheral intermediate signal band and central hyperintense signal on T2-weighted images, generally corresponding to the peripheral nodular enhancement and central non-enhancing portion on contrast-enhanced T1-weighted images, respectively.
软骨黏液样纤维瘤是一种罕见的原发性软骨良性骨肿瘤。尽管具有典型的影像学表现，但具有非典型影像学表现的软骨黏液样纤维瘤可能会模仿更常见的肿瘤。
描述软骨黏液样纤维瘤的磁共振成像（MR）表现。
回顾性分析19例经组织病理学证实的软骨黏液样纤维瘤的MR图像，观察其信号强度、骨膜反应、相邻异常骨髓和软组织信号以及对比增强模式。
所有软骨黏液样纤维瘤病例在T1加权图像上均表现为低信号至中等信号强度，7例（37%）可见内部高信号灶。在T2加权图像上，所有病变均为高信号：19个病变中有11个（58%）表现为外周中等信号带伴中央高信号，8个（42%）表现为弥漫性高信号且信号不均匀。19例中有11例（58%）观察到骨膜反应。19例中分别有12例（63%）和14例（74%）观察到相邻异常骨髓或软组织信号。在对比增强T1加权图像上，69%（11/16）表现为外周结节状强化，31%（5/16）表现为弥漫性对比增强，强化模式均匀（n = 3）或不均匀（n = 2）。在具有外周结节状强化的病例中，外周结节状强化部分通常对应于T2加权图像上的外周中等信号带，尽管外周强化不如中等信号强度带宽。另一方面，中央无强化部分通常对应于T2加权图像上的中央高信号强度。
软骨黏液样纤维瘤的特征性表现为T2加权图像上的外周中等信号带和中央高信号，分别对应于对比增强T1加权图像上的外周结节状强化和中央无强化部分。
