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软骨黏液样纤维瘤的治疗:一家机构22例病例的经验

Chondromyxoid fibroma management: a single institution experience of 22 cases.

作者信息

Bhamra Jagmeet S, Al-Khateeb Hesham, Dhinsa Baljinder S, Gikas Panos D, Tirabosco Roberto, Pollock Robin C, Skinner John A, Aston William J, Saifuddin Asif, Briggs Timothy Wr

机构信息

Bone Tumour Unit, The Royal National Orthopaedic Hospital, Stanmore, Middlesex HA7 4LP, UK.

出版信息

World J Surg Oncol. 2014 Sep 12;12:283. doi: 10.1186/1477-7819-12-283.

Abstract

BACKGROUND

Several different strategies have been reported for the treatment of chondromyxoid fibromas, all with variable outcomes and high recurrence rates.

METHODS

We report on 22 consecutive cases of chondromyxoid fibromas treated by intralesional curettage, four of which had adjuvant cementation at our institution between 2003 and 2010. We assessed the functional outcome using the Musculoskeletal Tumour Society (MSTS) scoring system.

RESULTS

Nine males and 16 females with a mean age of 36.5 years (range 11 to 73) and a mean follow-up of 60.7 months were included in the study. Local recurrence occurred in two patients (9%) within the first 2 years following the index procedure. This was treated by re-curettage only of the residual defect. Two postoperative complications occurred: a superficial wound infection in one patient and a transient deep peroneal nerve neurapraxia in the other. The mean postoperative MSTS score was 96.7%.

CONCLUSIONS

Intralesional curettage and cementation is as an effective treatment strategy for chondromyxoid fibromas, providing satisfactory functional results with a low recurrence rate. Careful case selection with stringent clinical and radiographic follow-up is recommended.

摘要

背景

已有多种不同的策略用于治疗软骨黏液样纤维瘤,但其结果各异且复发率高。

方法

我们报告了22例经病灶内刮除术治疗的软骨黏液样纤维瘤连续病例,其中4例在2003年至2010年间于本机构接受了辅助性骨水泥填充。我们使用肌肉骨骼肿瘤学会(MSTS)评分系统评估功能结果。

结果

本研究纳入了9例男性和16例女性,平均年龄36.5岁(范围11至73岁),平均随访60.7个月。2例患者(9%)在初次手术后的头2年内出现局部复发。仅对残留缺损进行再次刮除术治疗。发生了2例术后并发症:1例患者出现浅表伤口感染,另1例出现短暂性腓深神经失用症。术后MSTS评分的平均值为96.7%。

结论

病灶内刮除术和骨水泥填充是治疗软骨黏液样纤维瘤的有效策略,能提供满意的功能结果且复发率低。建议进行仔细的病例选择并进行严格的临床和影像学随访。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c3f/4247711/a31270a5a5aa/12957_2013_1816_Fig1_HTML.jpg

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