Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
AJNR Am J Neuroradiol. 2011 Sep;32(8):1469-73. doi: 10.3174/ajnr.A2595. Epub 2011 Aug 11.
Although often asymptomatic, enlarging sacral arachnoid cysts can also cause significant discomfort. These symptomatic sacral arachnoid cysts require specific treatments to facilitate local decompression. The main drawback of the surgical managements is the high risk of recurrence and complications. To decrease risks, we had been attempting to seek a simple and safe method to manage the symptomatic sacral arachnoid cysts. CT-guided percutaneous fibrin glue therapy is a new nonsurgical alternative. To evaluate the efficacy of the novel nonsurgical approach, we conducted this retrospective study of 38 patients.
Thirty-eight patients with symptomatic sacral arachnoid cysts underwent fibrin glue therapy in our hospital between June 2006 and May 2009. The clinical results of improvement in pain and neurologic function were evaluated after an average of 25 months of follow-up, and changes on the imaging findings were evaluated. Preoperative and postoperative pain severity was assessed according to a 10-cm VAS. Moreover, we also analyzed the postoperative complications.
Most patients experienced some degree of pain relief and functional improvement after fibrin glue therapy, with most experiencing complete or marked resolution of clinical symptoms. Twenty-one patients (55.3%) reported excellent recovery, 12 (31.5%) reported good recovery, 4 (10.5%) reported fair recovery, and 1 (2.6%) reported poor recovery. The overall percentage of positive outcomes (excellent and good recovery) was 86.8%. No serious postoperative complications were discovered.
CT-guided percutaneous injection of fibrin glue therapy is simple, safe, and effective for the management of symptomatic sacral arachnoid cysts.
尽管骶骨蛛网膜囊肿通常无症状，但也可能引起明显不适。这些有症状的骶骨蛛网膜囊肿需要特定的治疗方法来促进局部减压。手术治疗的主要缺点是复发和并发症的风险较高。为了降低风险，我们一直在尝试寻求一种简单、安全的方法来治疗有症状的骶骨蛛网膜囊肿。CT 引导下经皮纤维蛋白胶治疗是一种新的非手术选择。为了评估这种新的非手术方法的疗效，我们对 38 例患者进行了回顾性研究。
2006 年 6 月至 2009 年 5 月期间，我院对 38 例有症状的骶骨蛛网膜囊肿患者进行了纤维蛋白胶治疗。平均随访 25 个月后，评估疼痛和神经功能改善的临床效果，并评估影像学发现的变化。根据 10cm VAS 评估术前和术后疼痛严重程度。此外，我们还分析了术后并发症。
大多数患者在纤维蛋白胶治疗后疼痛程度有所缓解，功能有所改善，大多数患者的临床症状完全或明显缓解。21 例（55.3%）患者恢复良好，12 例（31.5%）患者恢复良好，4 例（10.5%）患者恢复一般，1 例（2.6%）患者恢复较差。总有效率（良好和恢复良好）为 86.8%。未发现严重的术后并发症。
CT 引导下经皮注射纤维蛋白胶治疗是一种简单、安全、有效的治疗有症状的骶骨蛛网膜囊肿的方法。
