Department of Psychiatry, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Indian J Psychiatry. 2010 Jan;52(Suppl 1):S355-61. doi: 10.4103/0019-5545.69265.
Mood stabilizers have revolutionized the treatment of bipolar affective disorders. We review data originating from India in the form of efficacy, effectiveness, usefulness, safety and tolerability of mood stabilizers. Data is mainly available for the usefulness and side-effects of lithium. A few studies in recent times have evaluated the usefulness of carbamazepine, valproate, atypical antipsychotics and verapamil. Occasional studies have compared two mood stabilizers. Data for long term efficacy and safety is conspicuously lacking.
心境稳定剂彻底改变了双相情感障碍的治疗方法。我们以疗效、有效性、实用性、安全性和耐受性的形式综述了来自印度的相关数据。数据主要可用于评估锂的实用性和副作用。最近有一些研究评估了卡马西平、丙戊酸盐、非典型抗精神病药和维拉帕米的实用性。偶尔也有研究比较了两种心境稳定剂。关于长期疗效和安全性的数据明显缺乏。
