, , Department of Psychiatry, National Institute of Mental Health and Neuro Sciences, Bangalore.
Indian J Psychiatry. 1980 Jul;22(3):304-6.
A case of a young manic patient who developed severe neurotoxicity when on lithium alone has been presented. Investigations did not reveal presence of any infection, electrolyte imbalance or rise in lithium level.The possibility of lithium producing neurotoxicity at therapeutic levels for as yet unknown reasons is pointed out. It is suggested that this element of risk be considered when starting lithium for therapy or prophylaxis of affective disorders.
现报道 1 例年轻躁狂症患者,仅服用锂盐时发生严重神经毒性。检查未发现任何感染、电解质失衡或锂水平升高。提示锂在治疗水平下产生神经毒性的可能性原因不明。建议在开始锂盐治疗或预防情感障碍时考虑这种风险因素。