Moumou Mohamed, Benharref Ahmed, Berraho Moha, El Ammari Lahcen, Akssira Mohamed, Elhakmaoui Ahmed
Acta Crystallogr Sect E Struct Rep Online. 2011 Jul 1;67(Pt 7):o1760-1. doi: 10.1107/S160053681102352X. Epub 2011 Jun 22.
The title compound, C(15)H(20)O(4), was synthesized from 9α-hy-droxy-parthenolide (9α-hy-droxy-4,8-dimethyl-12-methyl-ene-3,14-dioxatricyclo-[9.3.0.0(2,4)]tetra-dec-7-en-13-one), which was isolated from the chloro-form extract of the aerial parts of Anvillea radiata. The seven-membered ring has a chair conformation, while the five-membered rings display twisted conformations. The dihedral angle between the seven-membered ring and the lactone ring is 21.69 (10)°. In the crystal, mol-ecules are linked into chains propagating along the c axis by inter-molecular O-H⋯O hydrogen bonds; an intra-molecular O-H⋯O link also occurs.
标题化合物C(15)H(20)O(4)由9α-羟基-小白菊内酯（9α-羟基-4,8-二甲基-12-亚甲基-3,14-二氧杂三环-[9.3.0.0(2,4)]十四碳-7-烯-13-酮）合成，该化合物从辐射安维尔菊地上部分的氯仿提取物中分离得到。七元环具有椅式构象，而五元环呈现扭曲构象。七元环与内酯环之间的二面角为21.69 (10)°。在晶体中，分子通过分子间O-H⋯O氢键连接成沿c轴延伸的链；还存在分子内O-H⋯O连接。
