• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

1-苄基-1H-苯并咪唑-2(3H)-酮

1-Benzyl-1H-benzimidazol-2(3H)-one.

作者信息

Ouzidan Younes, Essassi El Mokhtar, Luis Santiago V, Bolte Michael, El Ammari Lahcen

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2011 Jul 1;67(Pt 7):o1822. doi: 10.1107/S160053681102455X. Epub 2011 Jun 25.

DOI:10.1107/S160053681102455X
PMID:21837191
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3151763/
Abstract

The fused five- and six-membered rings in the title compound, C(14)H(12)N(2)O, are essentially planar, the largest deviation from the mean plane being 0.023 (2) Å. The dihedral angle between the benzimidazole mean plane and the phenyl ring is 68.50 (6)°. In the crystal, each mol-ecule is linked to its symmetry equivalent created by a crystallographic inversion center by pairs of N-H⋯O hydrogen bonds, forming inversion dimers.

摘要

标题化合物C(14)H(12)N(2)O中稠合的五元环和六元环基本呈平面状，与平均平面的最大偏差为0.023 (2) Å。苯并咪唑平均平面与苯环之间的二面角为68.50 (6)°。在晶体中，每个分子通过N-H⋯O氢键对与其由晶体学倒转中心产生的对称等效物相连，形成倒转二聚体。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d4e9/3151763/98adc3914223/e-67-o1822-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d4e9/3151763/f26aaaf27fdd/e-67-o1822-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d4e9/3151763/98adc3914223/e-67-o1822-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d4e9/3151763/f26aaaf27fdd/e-67-o1822-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d4e9/3151763/98adc3914223/e-67-o1822-fig2.jpg

相似文献

1
1-Benzyl-1H-benzimidazol-2(3H)-one.1-苄基-1H-苯并咪唑-2(3H)-酮
Acta Crystallogr Sect E Struct Rep Online. 2011 Jul 1;67(Pt 7):o1822. doi: 10.1107/S160053681102455X. Epub 2011 Jun 25.
2
1-(4-Methyl-benz-yl)-1H-benzimidazol-2(3H)-one.1-（4-甲基-苄基）-1H-苯并咪唑-2（3H）-酮
Acta Crystallogr Sect E Struct Rep Online. 2013 Jan 1;69(Pt 1):o122. doi: 10.1107/S1600536812050726. Epub 2012 Dec 22.
3
3-Benzyl-6-bromo-1H-imidazo[4,5-b]pyridin-2(3H)-one.3-苄基-6-溴-1H-咪唑并[4,5-b]吡啶-2(3H)-酮
Acta Crystallogr Sect E Struct Rep Online. 2013 May 25;69(Pt 6):o962. doi: 10.1107/S1600536813013780. Print 2013 Jun 1.
4
1-Allyl-1H-1,3-benzimidazol-2(3H)-one.1-烯丙基-1H-1,3-苯并咪唑-2(3H)-酮
Acta Crystallogr Sect E Struct Rep Online. 2012 Nov 1;68(Pt 11):o3212. doi: 10.1107/S1600536812043620. Epub 2012 Oct 27.
5
1-Nonyl-1H-benzimidazol-2(3H)-one.1-壬基-1H-苯并咪唑-2(3H)-酮
Acta Crystallogr Sect E Struct Rep Online. 2011 Jan 8;67(Pt 2):o283. doi: 10.1107/S1600536810054164.
6
5-Chloro-1-nonyl-1H-benzimidazol-2(3H)-one.5-氯-1-壬基-1H-苯并咪唑-2(3H)-酮
Acta Crystallogr Sect E Struct Rep Online. 2011 Dec 1;67(Pt 12):o3340-1. doi: 10.1107/S1600536811047829. Epub 2011 Nov 16.
7
1-Allyl-6-nitro-1H-indazole.1-烯丙基-6-硝基-1H-吲唑
Acta Crystallogr Sect E Struct Rep Online. 2012 Dec 1;68(Pt 12):o3368. doi: 10.1107/S1600536812046478. Epub 2012 Nov 17.
8
1-Decyl-6-nitro-1H-benzimidazol-2(3H)-one.1-癸基-6-硝基-1H-苯并咪唑-2(3H)-酮
Acta Crystallogr Sect E Struct Rep Online. 2011 Nov;67(Pt 11):o2937. doi: 10.1107/S1600536811041389. Epub 2011 Oct 12.
9
3-Benzyl-1-{[3-(4-chloro-phen-yl)isoxazol-5-yl]meth-yl}-1H-benzimidazol-2(3H)-one.3-苄基-1-{[3-(4-氯苯基)异恶唑-5-基]甲基}-1H-苯并咪唑-2(3H)-酮
Acta Crystallogr Sect E Struct Rep Online. 2013 Aug 17;69(Pt 9):o1451. doi: 10.1107/S160053681302299X. eCollection 2013.
10
3-Allyl-6-bromo-1H-imidazo[4,5-b]pyridin-2(3H)-one.3-烯丙基-6-溴-1H-咪唑并[4,5-b]吡啶-2(3H)-酮
Acta Crystallogr Sect E Struct Rep Online. 2011 Aug 1;67(Pt 8):o1998. doi: 10.1107/S1600536811025037. Epub 2011 Jul 9.

引用本文的文献

1
Polymorphic structures of 3-phenyl-1-1,3-benzo-diazol-2(3)-one.3-苯基-1,3-苯并二氮杂卓-2(3)-酮的多晶型结构
Acta Crystallogr E Crystallogr Commun. 2023 May 12;79(Pt 6):534-537. doi: 10.1107/S2056989023003961. eCollection 2023 May 1.
2
Crystal structure of 1-methyl-4-methyl-sulfanyl-1H-pyrazolo-[3,4-d]pyrimidine.1-甲基-4-甲硫基-1H-吡唑并-[3,4-d]嘧啶的晶体结构
Acta Crystallogr Sect E Struct Rep Online. 2014 Nov 21;70(Pt 12):o1281. doi: 10.1107/S1600536814025239. eCollection 2014 Dec 1.
3
4-Benzyl-sulfanyl-1H-pyrazolo-[3,4-d]pyrimidine.

本文引用的文献

1
1,3-Bis[2-(2-oxo-1,3-oxazolidin-3-yl)eth-yl]-1H-benzimidazol-2(3H)-one.1,3-双[2-(2-氧代-1,3-恶唑烷-3-基)乙基]-1H-苯并咪唑-2(3H)-酮
Acta Crystallogr Sect E Struct Rep Online. 2011 Jan 12;67(Pt 2):o362-3. doi: 10.1107/S1600536810052141.
2
1-Nonyl-1H-benzimidazol-2(3H)-one.1-壬基-1H-苯并咪唑-2(3H)-酮
Acta Crystallogr Sect E Struct Rep Online. 2011 Jan 8;67(Pt 2):o283. doi: 10.1107/S1600536810054164.
3
A short history of SHELX.SHELX简史。
4-苄基硫烷基-1H-吡唑并-[3,4-d]嘧啶
Acta Crystallogr Sect E Struct Rep Online. 2013 Oct 16;69(Pt 11):o1650. doi: 10.1107/S160053681302789X.
4
1-(4-Methyl-benz-yl)-1H-benzimidazol-2(3H)-one.1-（4-甲基-苄基）-1H-苯并咪唑-2（3H）-酮
Acta Crystallogr Sect E Struct Rep Online. 2013 Jan 1;69(Pt 1):o122. doi: 10.1107/S1600536812050726. Epub 2012 Dec 22.
5
1-Allyl-1H-1,3-benzimidazol-2(3H)-one.1-烯丙基-1H-1,3-苯并咪唑-2(3H)-酮
Acta Crystallogr Sect E Struct Rep Online. 2012 Nov 1;68(Pt 11):o3212. doi: 10.1107/S1600536812043620. Epub 2012 Oct 27.
6
1,3-Dibenzyl-1H-benzimidazol-2(3H)-one.1,3-二苄基-1H-苯并咪唑-2(3H)-酮
Acta Crystallogr Sect E Struct Rep Online. 2011 Dec 1;67(Pt 12):o3234. doi: 10.1107/S1600536811046071. Epub 2011 Nov 9.
7
1,3-Dibenzyl-5-chloro-1H-benzimidazol-2(3H)-one.1,3 - 二苄基 - 5 - 氯 - 1H - 苯并咪唑 - 2(3H) - 酮
Acta Crystallogr Sect E Struct Rep Online. 2011 Aug 1;67(Pt 8):o2136. doi: 10.1107/S1600536811029084. Epub 2011 Jul 23.
Acta Crystallogr A. 2008 Jan;64(Pt 1):112-22. doi: 10.1107/S0108767307043930. Epub 2007 Dec 21.
4
The combinatorial synthesis of bicyclic privileged structures or privileged substructures.双环优势结构或优势子结构的组合合成。
Chem Rev. 2003 Mar;103(3):893-930. doi: 10.1021/cr020033s.
5
Synthesis and biological activity of novel nonnucleoside inhibitors of HIV-1 reverse transcriptase. 2-Aryl-substituted benzimidazoles.新型HIV-1逆转录酶非核苷抑制剂的合成与生物活性。2-芳基取代苯并咪唑类化合物。
J Med Chem. 1997 Dec 19;40(26):4199-207. doi: 10.1021/jm970096g.
6
Substituted 2,5'-Bi-1H-benzimidazoles: topoisomerase I inhibition and cytotoxicity.取代的2,5'-联-1H-苯并咪唑：拓扑异构酶I抑制作用和细胞毒性。
J Med Chem. 1996 Feb 16;39(4):992-8. doi: 10.1021/jm950412w.
7
DNA-directed alkylating agents. 6. Synthesis and antitumor activity of DNA minor groove-targeted aniline mustard analogues of pibenzimol (Hoechst 33258).DNA 定向烷基化剂。6. 针对 DNA 小沟的匹苯齐莫（Hoechst 33258）苯胺氮芥类似物的合成及抗肿瘤活性
J Med Chem. 1994 Dec 9;37(25):4338-45. doi: 10.1021/jm00051a010.