• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

苄基 N-(1-{N'-[(E)-2-氯苄叉基]肼羰基}-2-羟基乙基)氨基甲酸酯

Benzyl N-(1-{N'-[(E)-2-chloro-benzyl-idene]hydrazinecarbon-yl}-2-hy-droxy-eth-yl)carbamate.

作者信息

de Souza Marcus V N, Pinheiro Alessandra C, Tiekink Edward R T, Wardell Solange M S V, Wardell James L

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2011 Jul 1;67(Pt 7):o1868-9. doi: 10.1107/S1600536811024895. Epub 2011 Jun 30.

DOI:10.1107/S1600536811024895
PMID:21837231
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3151956/
Abstract

The mol-ecule of the title compound, C(18)H(18)ClN(3)O(4), is twisted about the chiral C atom with the dihedral angle between the two amide residues being 87.8 (5)°, but, overall, it can be described as curved, with the benzene rings lying on the same side of the mol-ecule [dihedral angle = 62.8 (4)°]. The conformation about the imine bond [1.294 (7) Å] is E. In the crystal, a two-dimensional array in the ab plane is mediated by O-H⋯O and N-H⋯O hydrogen bonds as well as C-H⋯Cl inter-actions. The layers stack along the c-axis direction, being connected by C-H⋯.π contacts.

摘要

标题化合物C(18)H(18)ClN(3)O(4)的分子围绕手性碳原子扭曲，两个酰胺残基之间的二面角为87.8 (5)°，但总体上可描述为弯曲的，苯环位于分子的同一侧[二面角 = 62.8 (4)°]。亚胺键[1.294 (7) Å]的构象为E型。在晶体中，ab平面内的二维阵列由O-H⋯O和N-H⋯O氢键以及C-H⋯Cl相互作用介导。这些层沿着c轴方向堆叠，通过C-H⋯π接触相连。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3726/3151956/313b68b292ff/e-67-o1868-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3726/3151956/67b06540341c/e-67-o1868-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3726/3151956/43bf8ab76da6/e-67-o1868-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3726/3151956/313b68b292ff/e-67-o1868-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3726/3151956/67b06540341c/e-67-o1868-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3726/3151956/43bf8ab76da6/e-67-o1868-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3726/3151956/313b68b292ff/e-67-o1868-fig3.jpg

相似文献

1
Benzyl N-(1-{N'-[(E)-2-chloro-benzyl-idene]hydrazinecarbon-yl}-2-hy-droxy-eth-yl)carbamate.苄基 N-(1-{N'-[(E)-2-氯苄叉基]肼羰基}-2-羟基乙基)氨基甲酸酯
Acta Crystallogr Sect E Struct Rep Online. 2011 Jul 1;67(Pt 7):o1868-9. doi: 10.1107/S1600536811024895. Epub 2011 Jun 30.
2
tert-Butyl N-((1S)-2-hy-droxy-1-{N'-[(E)-2-hy-droxy-4-meth-oxy-benzyl-idene]hydrazinecarbon-yl}eth-yl)carbamate.叔丁基 N-((1S)-2-羟基-1-{N'-[(E)-2-羟基-4-甲氧基苄叉基]肼羰基}乙基)氨基甲酸酯。
Acta Crystallogr Sect E Struct Rep Online. 2011 Aug 1;67(Pt 8):o1888-9. doi: 10.1107/S1600536811025293. Epub 2011 Jul 2.
3
Benzyl N-(2-hy-droxy-1-{N'-[(1E)-2-hy-droxy-benzyl-idene]hydrazinecarbon-yl}eth-yl)carbamate.N-（2-羟基-1-{N'-[(1E)-2-羟基苄叉基]肼羰基}乙基）苄基氨基甲酸酯
Acta Crystallogr Sect E Struct Rep Online. 2011 Jul 1;67(Pt 7):o1866-7. doi: 10.1107/S1600536811025128. Epub 2011 Jun 30.
4
tert-Butyl N-((1S)-2-hy-droxy-1-{N'-[(1E)-4-meth-oxy-benzyl-idene]hydrazinecarbon-yl}eth-yl)carbamate.叔丁基 N-((1S)-2-羟基-1-{N'-[(1E)-4-甲氧基苄叉基]肼羰基}乙基)氨基甲酸酯
Acta Crystallogr Sect E Struct Rep Online. 2011 Jul 1;67(Pt 7):o1805-6. doi: 10.1107/S1600536811024263. Epub 2011 Jun 25.
5
Benzyl N-(1-{N'-[(E)-2,3-dihy-droxy-benzyl-idene]hydrazinecarbon-yl}-2-hy-droxy-eth-yl)carbamate dihydrate.苄基 N-(1-{N'-[(E)-2,3-二羟基亚苄基]肼羰基}-2-羟基乙基)氨基甲酸酯二水合物
Acta Crystallogr Sect E Struct Rep Online. 2011 Aug 1;67(Pt 8):o2155-6. doi: 10.1107/S1600536811029370. Epub 2011 Jul 30.
6
tert-Butyl N-{(1S)-1-[(2,4-dihy-droxy-benzyl-idene)hydrazinecarbon-yl]-2-hy-droxy-eth-yl}carbamate ethanol monosolvate.N-{(1S)-1-[(2,4-二羟基苄叉基)肼羰基]-2-羟基乙基}氨基甲酸叔丁酯乙醇单溶剂合物
Acta Crystallogr Sect E Struct Rep Online. 2011 Feb 9;67(Pt 3):o581-2. doi: 10.1107/S1600536811003795.
7
Benzyl N-((S)-2-hydr-oxy-1-{N'-[(E)-2-methoxy-benzyl-idene]hydrazinecarbon-yl}eth-yl)carbamate from synchrotron data.基于同步加速器数据的苄基 N-((S)-2-羟基-1-{N'-[(E)-2-甲氧基苄叉基]肼羰基}乙基)氨基甲酸酯
Acta Crystallogr Sect E Struct Rep Online. 2010 Mar 31;66(Pt 4):o1004-5. doi: 10.1107/S1600536810011463.
8
3-Chloro-N'-(3-eth-oxy-2-hy-droxy-benzyl-idene)benzohydrazide monohydrate.3-氯-N'-(3-乙氧基-2-羟基亚苄基)苯甲酰肼一水合物
Acta Crystallogr Sect E Struct Rep Online. 2011 Jan 15;67(Pt 2):o377. doi: 10.1107/S160053681100122X.
9
Benzyl N-[(S)-2-hy-droxy-1-({[(E)-2-hy-droxy-4-meth-oxy-benzyl-idene]hydrazin-yl}carbon-yl)eth-yl]carbamate.苄基 N-[(S)-2-羟基-1-({[(E)-2-羟基-4-甲氧基苄叉基]肼基}羰基)乙基]氨基甲酸酯
Acta Crystallogr Sect E Struct Rep Online. 2010 Nov 20;66(Pt 12):o3253-4. doi: 10.1107/S1600536810047720.
10
(E)-4-Hy-droxy-N'-(3-hy-droxy-4-meth-oxy-benzyl-idene)benzohydrazide.（E）-4-羟基-N'-（3-羟基-4-甲氧基苯亚甲基）苯甲酰肼
Acta Crystallogr Sect E Struct Rep Online. 2011 Oct 1;67(Pt 10):o2644-5. doi: 10.1107/S1600536811036579. Epub 2011 Sep 14.

引用本文的文献

1
Benzyl N-(1-{N'-[(E)-2,3-dihy-droxy-benzyl-idene]hydrazinecarbon-yl}-2-hy-droxy-eth-yl)carbamate dihydrate.苄基 N-(1-{N'-[(E)-2,3-二羟基亚苄基]肼羰基}-2-羟基乙基)氨基甲酸酯二水合物
Acta Crystallogr Sect E Struct Rep Online. 2011 Aug 1;67(Pt 8):o2155-6. doi: 10.1107/S1600536811029370. Epub 2011 Jul 30.
2
tert-Butyl N-((1S)-2-hy-droxy-1-{N'-[(E)-2-hy-droxy-4-meth-oxy-benzyl-idene]hydrazinecarbon-yl}eth-yl)carbamate.叔丁基 N-((1S)-2-羟基-1-{N'-[(E)-2-羟基-4-甲氧基苄叉基]肼羰基}乙基)氨基甲酸酯。
Acta Crystallogr Sect E Struct Rep Online. 2011 Aug 1;67(Pt 8):o1888-9. doi: 10.1107/S1600536811025293. Epub 2011 Jul 2.
3

本文引用的文献

1
tert-Butyl N-((1S)-2-hy-droxy-1-{N'-[(1E)-4-meth-oxy-benzyl-idene]hydrazinecarbon-yl}eth-yl)carbamate.叔丁基 N-((1S)-2-羟基-1-{N'-[(1E)-4-甲氧基苄叉基]肼羰基}乙基)氨基甲酸酯
Acta Crystallogr Sect E Struct Rep Online. 2011 Jul 1;67(Pt 7):o1805-6. doi: 10.1107/S1600536811024263. Epub 2011 Jun 25.
2
Benzyl N-[(S)-2-hy-droxy-1-({[(E)-2-hy-droxy-4-meth-oxy-benzyl-idene]hydrazin-yl}carbon-yl)eth-yl]carbamate.苄基 N-[(S)-2-羟基-1-({[(E)-2-羟基-4-甲氧基苄叉基]肼基}羰基)乙基]氨基甲酸酯
Acta Crystallogr Sect E Struct Rep Online. 2010 Nov 20;66(Pt 12):o3253-4. doi: 10.1107/S1600536810047720.
3
Benzyl N-(2-hy-droxy-1-{N'-[(1E)-2-hy-droxy-benzyl-idene]hydrazinecarbon-yl}eth-yl)carbamate.
N-（2-羟基-1-{N'-[(1E)-2-羟基苄叉基]肼羰基}乙基）苄基氨基甲酸酯
Acta Crystallogr Sect E Struct Rep Online. 2011 Jul 1;67(Pt 7):o1866-7. doi: 10.1107/S1600536811025128. Epub 2011 Jun 30.
Benzyl N-((S)-2-hydr-oxy-1-{N'-[(E)-2-methoxy-benzyl-idene]hydrazinecarbon-yl}eth-yl)carbamate from synchrotron data.
基于同步加速器数据的苄基 N-((S)-2-羟基-1-{N'-[(E)-2-甲氧基苄叉基]肼羰基}乙基)氨基甲酸酯
Acta Crystallogr Sect E Struct Rep Online. 2010 Mar 31;66(Pt 4):o1004-5. doi: 10.1107/S1600536810011463.
4
tert-Butyl N-{(1S)-1-[(2,4-dihy-droxy-benzyl-idene)hydrazinecarbon-yl]-2-hy-droxy-eth-yl}carbamate ethanol monosolvate.N-{(1S)-1-[(2,4-二羟基苄叉基)肼羰基]-2-羟基乙基}氨基甲酸叔丁酯乙醇单溶剂合物
Acta Crystallogr Sect E Struct Rep Online. 2011 Feb 9;67(Pt 3):o581-2. doi: 10.1107/S1600536811003795.
5
Total synthesis of (+)-conagenin.(+)-贝壳杉烯二醇的全合成。
J Asian Nat Prod Res. 2009;11(3):274-80. doi: 10.1080/10286020902828369.
6
A short history of SHELX.SHELX简史。
Acta Crystallogr A. 2008 Jan;64(Pt 1):112-22. doi: 10.1107/S0108767307043930. Epub 2007 Dec 21.