Flinders Clinical Effectiveness, Flinders University, Bedford Park, SA, Australia.
Qual Life Res. 2012 May;21(4):717-25. doi: 10.1007/s11136-011-9971-y. Epub 2011 Aug 12.
To assess the construct validity of the CHU9D in an adolescent general population sample. The CHU9D is a new generic preference-based measure of health-related quality of life developed specifically for application in the economic evaluation of health care treatments and interventions for young people.
A web-based survey was developed including the CHU9D and HUI2 instruments and administered to a community-based sample of consenting adolescents (n = 710) aged 11-17 years. The practicality, face and construct validity of the CHU9D was examined. The relationship between the CHU9D and HUI2 instruments was assessed by a comparison of responses to similar dimensions and the utility scores derived from the two instruments.
The CHU9D demonstrated high completion rates. CHU9D was able to discriminate between respondents according to their self-reported general health (Kruskal-Wallis P value <0.001). The mean CHU9D adolescent population utilities were similar to those generated from the HUI2 [Mean (SD) CHU9D utility 0.844 (0.102) and HUI2 utility 0.872 (0.138)], and the intra-class correlation coefficient indicated good levels of agreement overall (ICC = 0.742).
The findings from this study provide support for the practicality, face and construct validity of the CHU9D for application with adolescents aged 11-17 years.
在青少年普通人群样本中评估 CHU9D 的结构效度。CHU9D 是一种新的通用偏好健康相关生活质量衡量标准,专为在年轻人的医疗保健治疗和干预的经济评估中应用而开发。
开发了一个基于网络的调查,其中包括 CHU9D 和 HUI2 工具,并在同意的 11-17 岁青少年的社区样本中进行了管理。检验了 CHU9D 的实用性、表面效度和结构效度。通过比较对相似维度的反应和从两种工具得出的效用得分来评估 CHU9D 和 HUI2 工具之间的关系。
CHU9D 显示出较高的完成率。CHU9D 能够根据受访者的自我报告的总体健康状况进行区分(Kruskal-Wallis P 值<0.001)。CHU9D 青少年人群的平均效用与 HUI2 生成的效用相似[平均(SD)CHU9D 效用 0.844(0.102)和 HUI2 效用 0.872(0.138)],总体上 ICC 表明了良好的一致性(ICC=0.742)。
本研究的结果为 11-17 岁青少年应用 CHU9D 的实用性、表面效度和结构效度提供了支持。