Porat O
McMaster University, Hamilton, Ontario, Canada.
Mol Reprod Dev. 1990 Apr;25(4):400-8. doi: 10.1002/mrd.1080250414.
The effects of the male contraceptive gossypol on the motility of mammalian spermatozoa are reviewed. The role of sperm motility in the processes of fertilization and the effect of the drug on these processes determine its effectiveness as a contraceptive. The promising male contraceptive potential of gossypol is discussed in the context of the serious adverse effects of the agent.
本文综述了男性避孕药棉酚对哺乳动物精子活力的影响。精子活力在受精过程中的作用以及该药物对这些过程的影响决定了其作为避孕药的有效性。在考虑到棉酚严重不良反应的背景下,讨论了其作为男性避孕药的潜在前景。