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铀酰离子与面包酵母无机焦磷酸酶相互作用的动力学研究。

Kinetic studies of the interaction of uranyl ions with inorganic pyrophosphatase from baker's yeast.

作者信息

Bienwald B, Höhne W E

出版信息

Acta Biol Med Ger. 1978;37(7):1129-33.

PMID:218410
Abstract

Kinetic measurements were performed to test the effect of uranyl ions on the enzymatic hydrolysis of pyrophosphate. A strong inhibition of the enzyme was found. From a Dixon-plot an inhibition competitive to the substrate magnesium pyrophosphate and an inhibitory constant of Ki = 3 . 10(-7) M was deduced.

摘要

进行动力学测量以测试铀酰离子对焦磷酸酶促水解的影响。发现该酶受到强烈抑制。从狄克逊图中推断出对底物焦磷酸镁具有竞争性抑制作用,抑制常数Ki = 3×10⁻⁷ M。

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