Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York, USA.
Physiology (Bethesda). 2011 Aug;26(4):266-72. doi: 10.1152/physiol.00008.2011.
The intercalated cell of collecting ducts of the kidney is of two forms, the α form secretes acid, whereas the β form secretes HCO(3). Here, we review recent work that shows that the α form is derived from the β form and that the pathway is mediated by an extracellular matrix protein called hensin/DMBT1.
肾脏集合管闰细胞有两种形式，α 形式分泌酸，而 β 形式分泌 HCO(3)。在这里，我们回顾了最近的工作，表明 α 形式是由 β 形式衍生而来的，而途径是由一种叫做 hensin/DMBT1 的细胞外基质蛋白介导的。
