儿科重症监护病房中的社区获得性耐甲氧西林金黄色葡萄球菌感染
Community-associated methicillin-resistant Staphylococcus aureus infections in a pediatric intensive care unit.
作者信息
Menif Khaled, Bouziri Asma, Khaldi Ammar, Hamdi Asma, Belhadj Sarra, Borgi Aida, Fitouri Zahra, Ben Jaballah Najla
机构信息
Pediatric intensive care unit, Children's Hospital of Tunis, Tunisia.
出版信息
J Infect Dev Ctries. 2011 Aug 12;5(8):587-91. doi: 10.3855/jidc.1565.
INTRODUCTION
Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) infection is an increasing problem worldwide. In developing countries, there is little data on CA-MRSA infection in children. This study reviewed the clinical features and outcomes of children admitted in a Tunisian pediatric intensive care unit with severe CA-MRSA infections.
METHODOLOGY
Retrospective chart review of patients coded for CA-MRSA over 10 years.
RESULTS
There were 14 (0.32% of all admissions) patients identified with severe CA-MRSA infections. The median age was three months (range, 0.5-156 months). All patients had pulmonary involvement. Six children (42.8%) developed septic shock. Two (14.3%) patients had multifocal infection with deep venous thrombosis. Two (14.3%) patients died.
CONCLUSIONS
Severe CA-MRSA pneumonia dominated presentation. The mortality of CA-MRSA infection in our series is lower than that previously reported.
引言
社区获得性耐甲氧西林金黄色葡萄球菌（CA-MRSA）感染在全球范围内日益严重。在发展中国家，关于儿童CA-MRSA感染的数据很少。本研究回顾了突尼斯一家儿科重症监护病房收治的患有严重CA-MRSA感染儿童的临床特征和转归。
方法
对10年间编码为CA-MRSA的患者进行回顾性病历审查。
结果
共识别出14例（占所有入院患者的0.32%）患有严重CA-MRSA感染的患者。中位年龄为3个月（范围0.5 - 156个月）。所有患者均有肺部受累。6名儿童（42.8%）发生感染性休克。2名（14.3%）患者发生多灶性感染并伴有深静脉血栓形成。2名（14.3%）患者死亡。
结论
严重的CA-MRSA肺炎是主要表现形式。我们系列研究中CA-MRSA感染的死亡率低于先前报道。
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