Bhutia Pema Yoden, Gurung Shrijana, Yegneswaran Prakash Peralam, Pradhan Jagat, Pradhan Uttam, Peggy Tshering, Pradhan Prakash Kumar, Bhutia Chewang Doma
Department of Microbiology, Sir Thotub Namgyal Memorial Hospital, Gangtok, Sikkim, India.
J Infect Dev Ctries. 2011 Aug 12;5(8):603-8. doi: 10.3855/jidc.1305.
Sporotrichosis caused by the fungus Sporothrix schenckii has been widely reported from the northern Himalayan belt and the north eastern region of India. Three autochthonous cases of lymphocutaneous sporotrichosis from east and south districts of Sikkim are reported. Fluid aspirate from the nodulo-ulcerative lesions were sent for cytology and fungal culture. S. schenckii was isolated on culture and cytological examination in all three cases showed granulomatous reaction. Thermal dimorphism was demonstrated and animal pathogenicity testing was performed. Saturated solution of potassium iodide was used for treatment and the last case was treated with itraconazole and potassium iodide. Awareness of this disease and an extensive environmental study is required to understand the actual burden of this disease.
由申克孢子丝菌引起的孢子丝菌病在喜马拉雅山脉北部地带和印度东北部地区已有广泛报道。本文报告了锡金东部和南部地区三例皮肤淋巴管型孢子丝菌病的本地病例。从结节溃疡性病变中抽取的液体送去做细胞学检查和真菌培养。在所有三例病例中，培养分离出了申克孢子丝菌，细胞学检查显示有肉芽肿反应。证实了其温度双态性并进行了动物致病性试验。使用碘化钾饱和溶液进行治疗，最后一例同时使用伊曲康唑和碘化钾进行治疗。需要提高对这种疾病的认识并开展广泛的环境研究，以了解这种疾病的实际负担。
