Hu C, Radelli L, Scorza R, Bonara P, Perego R, Fantuzzi G
Institute of Internal Medicine, University of Milan, Italy.
Int J Immunopharmacol. 1990;12(2):193-7. doi: 10.1016/0192-0561(90)90053-p.
Natural killer (NK) activities of fresh and IL-2-precultured peripheral blood mononuclear cells (PBMC) were investigated in 13 elderly subjects before and after thymopentin (TP-5) treatment and in 12 age-matched controls. The NK activity of fresh PBMC was found to be significantly higher in subjects given TP-5 at 50 mg s.c. three times per week for one month. Conversely, this type of treatment with TP-5 did not significantly modify the cytotoxic capacity of IL-2-precultured PBMC.
