Klingenstein A, Mayer W J, Rueping J, Miller C, Kampik A, Mino De Kaspar H
Augenklinik der LMU, Klinikum der Universität München, Campus Innenstadt, Mathildenstr. 8, 80336, München, Deutschland.
Ophthalmologe. 2011 Dec;108(12):1164-7. doi: 10.1007/s00347-011-2408-8.
A 43-year-old woman presented with a 2-month history of contact lens-associated keratitis and corneal ulceration on the left eye. Without having isolated the pathogenic agent, a calculated anti-infective and anti-inflammatory therapy had already been administered with no signs of improvement. Filamentous fungi (Acremonium sp) were found in the scraping material and the contact lens solution. A keratoplasty à chaud was necessary despite immediate initiation of pathogen-specific therapy. Early identification of the pathogen via corneal debridement and culturing are standard procedures in order to initiate a specific therapy and prevent ulceration which can threaten the visual outcome.
一名43岁女性因左眼有2个月的隐形眼镜相关性角膜炎和角膜溃疡病史前来就诊。在未分离出病原体的情况下，已进行了经验性抗感染和抗炎治疗，但无改善迹象。在刮取物和隐形眼镜护理液中发现了丝状真菌（枝顶孢属）。尽管立即开始了针对病原体的治疗，但仍有必要进行热角膜移植术。通过角膜清创术和培养早期识别病原体是启动特异性治疗并预防可能威胁视力预后的溃疡的标准程序。
