Assisted Conception Unit and Centre for Pre-implantation Genetic Diagnosis, London, UK.
Reprod Biomed Online. 2011 Oct;23(4):407-10. doi: 10.1016/j.rbmo.2011.05.019. Epub 2011 Jun 30.
Multiple pregnancy (MP) is widely recognized as the single biggest risk to children born as a result of assisted reproduction treatment. There is an emerging trend in Europe and Canada to promote single-embryo transfer (SET). In this issue, Gleicher argues that twin pregnancies should not be seen as an unfavourable outcome of assisted reproduction treatment. He argues that SET policies 'make no sense' since they will aggravate already unsatisfactory population growth in some countries. He also argues that governmental intervention to impose SET policies, despite proving successful in reducing MP, are inappropriate. The overwhelming evidence in the literature indicates that his opinion is not supported by credible data. Views should be based on solid data rather than personal judgement. Governmental interventions to reduce twin pregnancies, as demonstrated previously in Belgium and now in Québec, have been successful. The risks of twin pregnancies are real and borne by women and children, not their doctors. Doctors managing infertile couples are no longer entitled to take risks with the health of the next generation.
多胎妊娠(MP)被广泛认为是辅助生殖治疗导致的儿童面临的最大风险。在欧洲和加拿大,有一种新兴趋势是提倡单胚胎移植(SET)。在本期中,Gleicher 认为双胞胎妊娠不应被视为辅助生殖治疗的不良结局。他认为 SET 政策“毫无意义”,因为它们将加剧一些国家已经不尽如人意的人口增长。他还认为,尽管政府干预实施 SET 政策在减少 MP 方面取得了成功,但这种干预是不恰当的。文献中的压倒性证据表明,他的观点没有得到可靠数据的支持。观点应该基于确凿的数据,而不是个人判断。减少双胞胎妊娠的政府干预,如之前在比利时和现在在魁北克所证明的那样,已经取得了成功。双胞胎妊娠的风险是真实存在的,由妇女和儿童承担,而不是他们的医生。管理不孕夫妇的医生不再有权为下一代的健康冒险。