Hiromura T, Nojima T, Morita Y, Choji K, Nakada K, Tsukamoto E, Irie G
Department of Radiology, Hokkaido University School of Medicine.
Nihon Igaku Hoshasen Gakkai Zasshi. 1990 Jan 25;50(1):40-7.
Ultrasonographic findings of 13 patients with cystic papillary carcinoma (CPC) of the thyroid gland were reviewed retrospectively correlating with pathologic findings. A 4-6 cm oval cystic structure with a 2-3 cm pedunculated projection of mass into the lumen was the characteristic sonographic findings of CPC. However, other sonographic findings of CPC simulated adenoma, nodular goiter or follicular carcinoma. Pathological investigation revealed that malignant cells tended more to be located in intracystic pedunculated mass and/or pericystic region than in the cyst wall. In most of the cases cyst walls were chiefly composed of granulomatous tissue with scattered malignant cells. These findings indicate that the needle biopsy should be done under ultrasonographic guidance to obtain sufficient material for accurate cytologic and/or pathologic diagnosis, thereby reducing the number of false negative cases.
回顾性分析了13例甲状腺囊性乳头状癌（CPC）患者的超声检查结果，并与病理结果进行了相关性分析。一个4 - 6厘米椭圆形囊性结构，有一个2 - 3厘米带蒂肿物突入管腔是CPC的特征性超声表现。然而，CPC的其他超声表现可类似腺瘤、结节性甲状腺肿或滤泡癌。病理检查发现，恶性细胞更多地倾向于位于囊内带蒂肿物和/或囊肿周围区域，而非囊肿壁。在大多数病例中，囊肿壁主要由肉芽肿组织组成，伴有散在的恶性细胞。这些发现表明，应在超声引导下进行针吸活检，以获取足够的材料进行准确的细胞学和/或病理诊断，从而减少假阴性病例的数量。
