Makusheva V P, Bakharev V D, Nikolaev S V, Lupanova G E
Probl Endokrinol (Mosk). 1990 Jan-Feb;36(1):72-4.
The paper is devoted to comparative analysis of the activity of peptides (LH-RH analogs) with relation to their action on ovulation as well as on the learning capabilities and their effect on immobilization stress in rats. The acceleration of learning processes and elimination of immobilization stress were shown to be caused by LH-RH and its analogs, regulating actively ovulation under experimental conditions. The comparative evaluation of their action has shown that LH-RH analogs-antagonists produce a more marked effect on the process of learning and elimination of stress consequences than its analogs-agonists.
本文致力于对肽(促黄体激素释放激素类似物)的活性进行比较分析,这些肽与它们对大鼠排卵、学习能力的作用以及对固定应激的影响有关。促黄体激素释放激素及其类似物在实验条件下积极调节排卵,研究表明它们可加速学习过程并消除固定应激。对它们作用的比较评估表明,促黄体激素释放激素类似物拮抗剂对学习过程和应激后果消除的影响比其类似物激动剂更为显著。