[Effect of a cyclic luliberin analog on ovulation].

A study was made of the cyclic LH-RH analog and its linear precursor on infantile and mature female rats. The compounds showed various biological properties which manifested themselves in their effects on ovulation. The linear analog proved to be an antagonist and the cyclic analog the LH-RH agonist. A hypothesis to the effect that the LH-RH biologically active conformation has a quasicyclic structure, has been confirmed.