• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

固体水 457 水当量平板中密度变化的剂量学影响。

Dosimetric impact of density variations in Solid Water 457 water-equivalent slabs.

机构信息

Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan, USA.

出版信息

J Appl Clin Med Phys. 2011 Apr 22;12(3):3398. doi: 10.1120/jacmp.v12i3.3398.

DOI:10.1120/jacmp.v12i3.3398
PMID:21844848
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5718651/
Abstract

The purpose of this study was to determine the dosimetric impact of density variations observed in water-equivalent solid slabs. Measurements were performed using two 30 cm × 30 cm water-equivalent slabs, one being 4 cm think and the other 5 cm thick. The location and extent of density variations were determined by computed tomography (CT) scans. Additional imaging measurements were made with an amorphous silicon megavoltage portal imaging device and an ultrasound unit. Dosimetric measurements were conducted with a 2D ion chamber array, and a scanned diode in water. Additional measurements and calculations were made of small rectilinear void inhomogeneities formed with water-equivalent slabs, using a 2D ion chamber array and the convolution superposition algorithm. Two general types of density variation features were observed on CT images: 1) regions of many centimeters across, but typically only a few millimeters thick, with electron densities a few percent lower than the bulk material, and 2) cylindrical regions roughly 0.2 cm in diameter and up to 20 cm long with electron densities up to 5% lower than the surrounding material. The density variations were not visible on kilovoltage, megavoltage or ultrasound images. The dosimetric impact of the density variations were not detectable to within 0.1% using the 2D ion chamber array or the scanning photon diode at distances 0.4 cm to 2 cm beyond the features. High-resolution dosimetric calculations using the convolution-superposition algorithm with density corrections enabled on CT-based datasets showed no discernable dosimetric impact. Calculations and measurements on simulated voids place the upper limit on possible dosimetric variations from observed density variations at much less than 0.6%. CT imaging of water-equivalent slabs may reveal density variations which are otherwise unobserved with kV, MV, or ultrasound imaging. No dosimetric impact from these features was measureable with an ion chamber array or scanned photon diode. Consequently, they were determined to be acceptable for all clinical use.

摘要

本研究旨在确定在水等效固体平板中观察到的密度变化对剂量的影响。使用两个 30 cm×30 cm 的水等效平板进行测量,一个厚度为 4 cm,另一个厚度为 5 cm。密度变化的位置和程度通过计算机断层扫描(CT)扫描确定。使用非晶硅兆伏级门成像设备和超声单元进行了额外的成像测量。使用二维离子室阵列和扫描二极管在水中进行了剂量学测量。使用二维离子室阵列和卷积叠加算法对水等效平板形成的小矩形空洞不均匀性进行了额外的测量和计算。在 CT 图像上观察到两种一般类型的密度变化特征:1)几厘米宽的区域,但通常只有几毫米厚,电子密度比基体材料低几个百分点,2)直径约 0.2 cm 且长达 20 cm 的圆柱形区域,电子密度比周围材料低高达 5%。在千伏、兆伏或超声图像上看不到密度变化。在距离特征 0.4 cm 至 2 cm 处,使用二维离子室阵列或扫描光子二极管,在 0.1%以内无法检测到密度变化的剂量学影响。使用基于 CT 的数据集进行密度校正的卷积叠加算法进行高分辨率剂量学计算显示,没有可察觉的剂量学影响。使用基于 CT 的数据集进行密度校正的卷积叠加算法进行高分辨率剂量学计算显示,没有可察觉的剂量学影响。使用基于 CT 的数据集进行密度校正的卷积叠加算法进行高分辨率剂量学计算显示,没有可察觉的剂量学影响。使用基于 CT 的数据集进行密度校正的卷积叠加算法进行高分辨率剂量学计算显示,没有可察觉的剂量学影响。使用基于 CT 的数据集进行密度校正的卷积叠加算法进行高分辨率剂量学计算显示,没有可察觉的剂量学影响。使用基于 CT 的数据集进行密度校正的卷积叠加算法进行高分辨率剂量学计算显示,没有可察觉的剂量学影响。计算和测量模拟空洞的结果将观察到的密度变化引起的可能剂量变化的上限限制在远小于 0.6%。水等效平板的 CT 成像可能会揭示其他 kV、MV 或超声成像无法观察到的密度变化。使用离子室阵列或扫描光子二极管无法测量这些特征的剂量学影响。因此,它们被确定为可用于所有临床用途。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5803/5718651/2e01624cb77a/ACM2-12-231-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5803/5718651/c8825bd3788b/ACM2-12-231-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5803/5718651/0be0399a6dc4/ACM2-12-231-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5803/5718651/ad67320ac9b3/ACM2-12-231-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5803/5718651/34015c23c4c0/ACM2-12-231-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5803/5718651/c75f18623c57/ACM2-12-231-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5803/5718651/f8df236e6306/ACM2-12-231-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5803/5718651/0a998679aed8/ACM2-12-231-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5803/5718651/2a3892d5605a/ACM2-12-231-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5803/5718651/fd41936084c7/ACM2-12-231-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5803/5718651/dcbca630291e/ACM2-12-231-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5803/5718651/4b4c0a4c5a50/ACM2-12-231-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5803/5718651/2e01624cb77a/ACM2-12-231-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5803/5718651/c8825bd3788b/ACM2-12-231-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5803/5718651/0be0399a6dc4/ACM2-12-231-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5803/5718651/ad67320ac9b3/ACM2-12-231-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5803/5718651/34015c23c4c0/ACM2-12-231-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5803/5718651/c75f18623c57/ACM2-12-231-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5803/5718651/f8df236e6306/ACM2-12-231-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5803/5718651/0a998679aed8/ACM2-12-231-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5803/5718651/2a3892d5605a/ACM2-12-231-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5803/5718651/fd41936084c7/ACM2-12-231-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5803/5718651/dcbca630291e/ACM2-12-231-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5803/5718651/4b4c0a4c5a50/ACM2-12-231-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5803/5718651/2e01624cb77a/ACM2-12-231-g012.jpg

相似文献

1
Dosimetric impact of density variations in Solid Water 457 water-equivalent slabs.固体水 457 水当量平板中密度变化的剂量学影响。
J Appl Clin Med Phys. 2011 Apr 22;12(3):3398. doi: 10.1120/jacmp.v12i3.3398.
2
Dosimetric comparison of extended dose range film with ionization measurements in water and lung equivalent heterogeneous media exposed to megavoltage photons.在水和肺等效非均匀介质中,对兆伏级光子照射下的扩展剂量范围胶片与电离测量进行剂量学比较。
J Appl Clin Med Phys. 2003 Winter;4(1):25-39. doi: 10.1120/jacmp.v4i1.2539.
3
Dosimetric investigation and portal dose image prediction using an amorphous silicon electronic portal imaging device.使用非晶硅电子射野影像装置进行剂量学研究和射野剂量影像预测。
Med Phys. 2001 Jun;28(6):911-24. doi: 10.1118/1.1374244.
4
Dosimetric validation of Acuros XB with Monte Carlo methods for photon dose calculations.利用蒙特卡罗方法对 Acuros XB 进行光子剂量计算的剂量学验证。
Med Phys. 2011 Apr;38(4):2208-21. doi: 10.1118/1.3567146.
5
High resolution 2D dose measurement device based on a few long scintillating fibers and tomographic reconstruction.基于几根长闪烁光纤和断层重建的高分辨率二维剂量测量装置。
Med Phys. 2012 Aug;39(8):4840-9. doi: 10.1118/1.4736526.
6
Evaluation of an a-Si EPID in direct detection configuration as a water-equivalent dosimeter for transit dosimetry.评估直接探测配置中的非晶硅 EPID 作为传输剂量学用水等效剂量计。
Med Phys. 2010 Apr;37(4):1459-67. doi: 10.1118/1.3327456.
7
Development of an accurate EPID-based output measurement and dosimetric verification tool for electron beam therapy.开发一种用于电子束治疗的基于电子射野影像装置的精确输出测量和剂量验证工具。
Med Phys. 2015 Jul;42(7):4190-8. doi: 10.1118/1.4922400.
8
Diamond detector versus silicon diode and ion chamber in photon beams of different energy and field size.不同能量和射野大小的光子束中钻石探测器与硅二极管及电离室的比较
Med Phys. 2003 Aug;30(8):2149-54. doi: 10.1118/1.1591431.
9
Dosimetric properties of an amorphous silicon EPID for verification of modulated electron radiotherapy.用于验证调强电子放射治疗的非晶硅 EPID 的剂量学特性。
Med Phys. 2013 Jun;40(6):061710. doi: 10.1118/1.4805113.
10
Use of a commercial ion chamber detector array for the measurement of high spatial-resolution photon beam profiles.使用商业离子室探测器阵列测量高空间分辨率光子束轮廓。
J Appl Clin Med Phys. 2018 Nov;19(6):323-331. doi: 10.1002/acm2.12466. Epub 2018 Oct 4.

引用本文的文献

1
Development of an Anthropomorphic Heterogeneous Female Pelvic Phantom and Its Comparison with a Homogeneous Phantom in Advance Radiation Therapy: Dosimetry Analysis.发展一种拟人化异性盆腔混合 phantom 及其在先进放射治疗中的与同质 phantom 比较:剂量学分析。
Med Sci (Basel). 2023 Sep 11;11(3):59. doi: 10.3390/medsci11030059.
2
Water equivalence of a solid phantom material for radiation dosimetry applications.用于辐射剂量学应用的固体模体材料的水等效性。
Phys Imaging Radiat Oncol. 2020 May 28;14:43-47. doi: 10.1016/j.phro.2020.05.003. eCollection 2020 Apr.

本文引用的文献

1
Accelerator beam data commissioning equipment and procedures: report of the TG-106 of the Therapy Physics Committee of the AAPM.加速器束流数据调试设备与程序:美国医学物理师协会治疗物理委员会TG - 106报告
Med Phys. 2008 Sep;35(9):4186-215. doi: 10.1118/1.2969070.
2
Characterization of the phantom material virtual water in high-energy photon and electron beams.高能光子束和电子束中体模材料虚拟水的特性描述
Med Phys. 2006 Apr;33(4):876-87. doi: 10.1118/1.2174186.
3
Absorbed dose to water reference dosimetry using solid phantoms in the context of absorbed-dose protocols.
在吸收剂量协议的背景下,使用固体模体进行水的吸收剂量参考剂量测定。
Med Phys. 2005 Sep;32(9):2945-53. doi: 10.1118/1.2012807.
4
AAPM's TG-51 protocol for clinical reference dosimetry of high-energy photon and electron beams.美国医学物理学家协会(AAPM)关于高能光子和电子束临床参考剂量测定的TG-51协议。
Med Phys. 1999 Sep;26(9):1847-70. doi: 10.1118/1.598691.
5
An evaluation of epoxy resin phantom materials for megavoltage photon dosimetry.
Phys Med Biol. 1999 May;44(5):1125-32. doi: 10.1088/0031-9155/44/5/001.
6
How water equivalent are water-equivalent solid materials for output calibration of photon and electron beams?对于光子束和电子束的输出校准,水等效固体材料的水等效性如何?
Med Phys. 1995 Jul;22(7):1177-89. doi: 10.1118/1.597613.
7
An evaluation of the recommendations of the TG-25 protocol for determination of depth dose curves for electron beams using ionization chambers.使用电离室对TG-25协议中关于电子束深度剂量曲线测定建议的评估。
Med Phys. 1995 Aug;22(8):1333-7. doi: 10.1118/1.597615.
8
A solid water phantom material for radiotherapy x-ray and gamma-ray beam calibrations.一种用于放射治疗X射线和γ射线束校准的固态水模体材料。
Med Phys. 1982 May-Jun;9(3):436-41. doi: 10.1118/1.595063.
9
Measurements of ionisation in water, polystyrene and a 'solid water' phantom material for electron beams.电子束在水、聚苯乙烯和一种“固体水”体模材料中的电离测量。
Phys Med Biol. 1985 Jan;30(1):41-53. doi: 10.1088/0031-9155/30/1/005.
10
Stopping-power and mass energy-absorption coefficient ratios for Solid Water.固体水的阻止本领和质量能量吸收系数比。
Med Phys. 1986 May-Jun;13(3):403-4. doi: 10.1118/1.595884.