Chemistry Research Laboratory, University of Oxford, Mansfield Rd, University of Oxford, Oxford, OX1 3TA, UK.
Org Biomol Chem. 2011 Oct 7;9(19):6663-9. doi: 10.1039/c1ob05816a. Epub 2011 Aug 16.
An efficient strategy for the control of the chemoselectivity in Dieckmann ring closures leading to tetramic acids derived from serine and α-methyl serine is reported, and this provides pathways to diversely substituted systems from a common starting material.
报道了一种用于控制 Dieckmann 环封闭中化学选择性的有效策略,该策略可得到源自丝氨酸和α-甲基丝氨酸的四氢酸,并且从共同的起始原料提供了通向多种取代的系统的途径。