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[肾活检评估:对肾病学家而言哪些信息很重要?]

[Evaluation of a renal biopsy: what information is important for nephrologists?].

作者信息

Amann K, Büttner M

机构信息

Abteilung Nephropathologie, Pathologisches Institut, Universität Erlangen-Nürnberg, Krankenhausstr. 12, 91054, Erlangen, Deutschland.

出版信息

Pathologe. 2011 Nov;32 Suppl 2:361-9. doi: 10.1007/s00292-011-1484-5.

DOI:10.1007/s00292-011-1484-5
PMID:21845359
Abstract

A kidney biopsy is an important and frequently used diagnostic tool in routine nephrology. In order to obtain relevant clinical information from a renal biopsy close cooperation between clinicians and pathologists is mandatory. The better the information obtained from nephrologists and the better the understanding by nephrologists and the quality of the kidney biopsy, the more rewarding is the information from pathologists. The following paper will discuss some practical aspects regarding the interaction between nephrology and pathology which may not be known or poorly handled and may thus cause misunderstanding. In order to facilitate interaction between clinicians and pathologists some guidelines concerning the procedure and work-up of routine kidney biopsies have been established and will be discussed in detail.

摘要

肾活检是常规肾脏病学中一项重要且常用的诊断工具。为了从肾活检中获取相关临床信息,临床医生和病理学家之间的密切合作必不可少。从肾病学家处获得的信息越好,肾病学家的理解越到位,肾活检的质量越高,病理学家提供的信息就越有价值。以下文章将讨论肾脏病学与病理学之间相互作用的一些实际问题,这些问题可能不为人知或处理不当,从而可能导致误解。为了促进临床医生和病理学家之间的互动,已经制定了一些关于常规肾活检程序和检查的指南,并将进行详细讨论。

相似文献

1
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Pathologe. 2011 Nov;32 Suppl 2:361-9. doi: 10.1007/s00292-011-1484-5.
2
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本文引用的文献

1
Transvenous renal biopsy of a kidney transplant in a patient with a suspected bleeding disorder.对一名疑似有出血性疾病的肾移植患者进行经静脉肾活检。
Am J Transplant. 2007 Aug;7(8):2052-3. doi: 10.1111/j.1600-6143.2007.01865.x. Epub 2007 May 25.
2
Interstitial vascular rarefaction and reduced VEGF-A expression in human diabetic nephropathy.人类糖尿病肾病中的间质血管稀疏及血管内皮生长因子-A表达降低
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3
Gene-expression profiles and age of donor kidney biopsies obtained before transplantation distinguish medium term graft function.
移植前获取的供体肾活检组织的基因表达谱和年龄可区分中期移植肾功能。
Transplantation. 2007 Apr 27;83(8):1048-54. doi: 10.1097/01.tp.0000259960.56786.ec.
4
Lymphatic neoangiogenesis in human renal allografts: results from sequential protocol biopsies.人肾移植中淋巴管新生:序贯方案活检结果
Am J Transplant. 2007 Feb;7(2):377-84. doi: 10.1111/j.1600-6143.2006.01638.x.
5
Protocol biopsies in renal transplantation: insights into patient management and pathogenesis.肾移植中的协议活检:对患者管理和发病机制的见解
Am J Transplant. 2007 Mar;7(3):512-7. doi: 10.1111/j.1600-6143.2006.01677.x. Epub 2007 Jan 22.
6
The contribution of quantitative techniques including morphometry to renal diagnosis.包括形态测量学在内的定量技术对肾脏诊断的贡献。
Ultrastruct Pathol. 2006 Sep-Oct;30(5):339-43. doi: 10.1080/01913120600932537.
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Modular activation of nuclear factor-kappaB transcriptional programs in human diabetic nephropathy.人类糖尿病肾病中核因子-κB转录程序的模块化激活
Diabetes. 2006 Nov;55(11):2993-3003. doi: 10.2337/db06-0477.
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Protein biomarkers associated with acute renal failure and chronic kidney disease.与急性肾衰竭和慢性肾病相关的蛋白质生物标志物。
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Gene expression profiling analysis in nephrology: towards molecular definition of renal disease.肾脏病学中的基因表达谱分析:迈向肾脏疾病的分子定义
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