Kashgarian Michael
Yale University, New Haven, Connecticut 06520-8023, USA.
Ultrastruct Pathol. 2006 Sep-Oct;30(5):339-43. doi: 10.1080/01913120600932537.
The use of quantitative techniques in diagnostic renal pathology has not been utilized fully because of the relative inaccessibility and complexity of using statistically valid stereologic techniques. The introduction of digital image capture and computer-assisted image analysis has opened a new door to the analysis of renal biopsies. The potential of quantitative information to give greater prognostic information or better insight into the pathogenesis of many of these lesions is yet to be completely elucidated. Digital imaging and the advent of virtual microscopy should open new avenues of investigation into the pathogenesis of renal disease using clinically obtained renal biopsy material.
由于使用具有统计学有效性的体视学技术相对困难且复杂，定量技术在诊断性肾脏病理学中的应用尚未得到充分利用。数字图像采集和计算机辅助图像分析的引入为肾活检分析打开了一扇新的大门。定量信息在提供更多预后信息或更好地洞察许多此类病变发病机制方面的潜力尚未完全阐明。数字成像和虚拟显微镜的出现应该为利用临床获取的肾活检材料研究肾脏疾病的发病机制开辟新的途径。
