Scientific Direction, IRCCS San Raffaele Pisana. Via di Val Cannuta, 247, 00166, Rome, Italy.
Int J Geriatr Psychiatry. 2011 Sep;26(9):916-22. doi: 10.1002/gps.2624. Epub 2010 Dec 9.
Personality changes are known to occur in idiopathic Parkinson's Disease (PD). The aim of the study was to evaluate whether religious and spiritual beliefs in PD patients are different from age-matched controls.
Eighty-three PD participants, 79 hypertensive individuals not affected by PD and 88 healthy subjects participated to a cross-sectional study. The Royal Free Interview (RFI) was used to evaluate participants' beliefs. The Hospital Anxiety and Depression Scale (HADS) was applied to monitor emotional distress.
There was no statistical evidence of a difference between PD participants and the two control groups, the only exception being observed between the left PD onset group and the controls, where the total RFI score was about 5 points higher (t-test: p = 0.0273). RFI total score was uncorrelated with age, severity of illness and depression, but was strongly dependent on the type of beliefs. The percentage of PD participants suffering from anxiety and depression was high (right onset: 54.8%; left onset: 68.6%), while only 15.2% of the hypertensive participants, and none of the healthy controls, had a HADS score above 10 points. Total RFI score was higher in women.
PD participants maintain their Faith in spite of the disease severity. Differences are found between right and left onset of PD. The possible beneficial effect of religious coping is discussed.
特发性帕金森病（PD）患者会出现人格变化。本研究旨在评估 PD 患者的宗教和精神信仰是否与年龄匹配的对照组不同。
83 名 PD 参与者、79 名未患 PD 的高血压个体和 88 名健康受试者参与了一项横断面研究。使用皇家自由访谈（RFI）评估参与者的信仰。采用医院焦虑和抑郁量表（HADS）监测情绪困扰。
PD 参与者与两组对照组之间没有统计学证据表明存在差异，唯一的例外是左 PD 发病组与对照组之间，总 RFI 评分高出约 5 分（t 检验：p=0.0273）。RFI 总分与年龄、疾病严重程度和抑郁无关，但与信仰类型密切相关。焦虑和抑郁的 PD 参与者比例较高（右发病：54.8%；左发病：68.6%），而高血压参与者中只有 15.2%，健康对照组中没有一个人的 HADS 评分超过 10 分。RFI 总分在女性中较高。
PD 患者尽管病情严重，但仍保持信仰。PD 的右发病和左发病之间存在差异。讨论了宗教应对可能产生的有益影响。
