某些遗传标记在预测锂治疗反应中的效用。
Utility of some genetic marker in predicting response to lithium.
机构信息
Psychiatrist, Department of Psychiatry, NIMHANS, Bangalore.
出版信息
Indian J Psychiatry. 1983 Apr;25(2):94-7.
Abstract
One hundred manic patients who were treated with lithium were studied to find out the possibility of genetic variations in response to lithium. Along with pedigree study, test of colour blindness and ABO blood grouping were used as genetic markers. The study supports the transmission by autosomal dominance with incomplete penetrance. There is no difference between the responders and non-responders in the mode of transmission and in the family history of mental illness, ABO blood grouping.
摘要
对 100 名接受锂治疗的躁狂症患者进行了研究，以探讨锂治疗反应的遗传变异的可能性。除了家系研究外，还使用色盲测试和 ABO 血型作为遗传标记。该研究支持常染色体显性遗传伴不完全外显。在遗传方式和精神疾病家族史、ABO 血型方面，应答者和无应答者之间没有差异。
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