抑郁症患者的尿褪黑素。
Urinary melatonin in depression.
机构信息
Professor & Head, Institute of Psychiatry, Madurai Medical College & Govt. Rajaji Hospital, Madurai.
出版信息
Indian J Psychiatry. 1983 Jul;25(3):167-72.
This report is based on a study of 12 cases of depression (8 endogenous, 4 neurotic) with a view to explore the possible association between urinary melatonin and the illness prior to and following treatment. While cases of endogenous depression had low 24 hour as well as nocturnal urinary melatonin levels, the neurotic depressives showed higher than normal levels. A rise in the 24 hour melatonin levels occurred in all cases of endogenous depression though this did not apply, to the nocturnal levels. An association between melatonin levels with suicide behaviour, insomnia, psychomotor retardation and diurnal variation is discussed.
本报告基于对 12 例抑郁症患者（8 例内源性，4 例神经症性）的研究，旨在探讨治疗前后尿褪黑素与疾病之间的可能关联。虽然内源性抑郁症患者的 24 小时和夜间尿褪黑素水平较低，但神经症性抑郁症患者的水平则高于正常水平。所有内源性抑郁症患者的 24 小时褪黑素水平均升高，但夜间水平则不然。还讨论了褪黑素水平与自杀行为、失眠、精神运动迟缓以及昼夜节律变化之间的关系。
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