Koca Çalişkan Ufuk, Aka Ceylan, Bor Emrah
Gazi University, Faculty Of Pharmacy, Department Of Pharmacognosy, Ankara, Turkey.
Turk J Pharm Sci. 2017 Apr;14(1):75-83. doi: 10.4274/tjps.33043. Epub 2017 Apr 15.
The concept of melatonin has become more important recently both in plants and in human who utilize plants for nutritional and health purposes. Melatonin, synthesized from L-tryptophan by enzyms, protects plants against difficult conditions. People have consumed these plants for their antioxidant, immunomodulator, antiinflammatory and anticancer effects. In parts of edible and non-edible plants, levels of melatonin are determined by cyclodextrin-modified micellar electrokinetic chromatography, enzyme-linked immuno sorbent assay, radioimmunoassay, high-performance liquid chromatography, liquid chromatography with electrochemical detection, liquid chromatography with fluorimetric detection, liquid chromatography-mass spectrometry, and liquid chromatography-ultraviolet spectrophotometry. In this review, biosynthesis of melatonin in both animal and plants, function of melatonin in plant kingdom, especially in medicinal/edible and nonedible plants, and detection of phytomelatonin content in those plants are presented.
褪黑素的概念最近在植物以及将植物用于营养和健康目的的人类中变得更加重要。褪黑素由酶从L-色氨酸合成,可保护植物免受恶劣条件的影响。人们食用这些植物是因其具有抗氧化、免疫调节、抗炎和抗癌作用。在可食用和不可食用植物的部分中,褪黑素的含量通过环糊精修饰的胶束电动色谱法、酶联免疫吸附测定法、放射免疫测定法、高效液相色谱法、电化学检测液相色谱法、荧光检测液相色谱法、液相色谱-质谱联用以及液相色谱-紫外分光光度法来测定。在这篇综述中,介绍了动物和植物中褪黑素的生物合成、褪黑素在植物界的功能,特别是在药用/可食用和不可食用植物中的功能,以及这些植物中植物褪黑素含量的检测。