Baharivand Nader, Hariri Amirhossein, Javadzadeh Alireza, Heidari Ebadollah, Sadegi Karim
Nikookari Eye Hospital, Tabriz University of Medical Sciences, Tabriz, Iran.
Clin Ophthalmol. 2011;5:1089-93. doi: 10.2147/OPTH.S23164. Epub 2011 Aug 5.
To evaluate the effects of vitrectomy and internal limiting membrane peeling for treatment of macular edema secondary to retinal vein occlusion (RVO).
Nine cases of visual loss due to macular edema caused by central retinal vein occlusion or branch retinal vein occlusion underwent pars plana vitrectomy with removal of the preretinal hyaloid, peeling of the internal limiting membrane stained with indocyanine green dye, air-fluid exchange, and postoperative prone positioning. Best-corrected visual acuity (BCVA) and central foveal thickness by optical coherence tomography were measured pre- and postoperatively then compared to assess the outcome of surgery.
In all cases intraretinal blood and retinal thickening diminished within 2 months of surgery. Visual acuity improved in all of the central retinal vein occlusion cases and 3/6 branch retinal vein occlusion cases. The decrease in macular thickness was statistically significant (mean postoperative macular thickness 361 ± 61.1 versus mean preoperative macular thickness 563.9 ± 90.0, P = 0.001, t-test). The improvement in BCVA was not statistically significant (mean preoperative BCVA in LogMAR 1.23 ± 0.29 versus mean postoperative BCVA in LogMAR 1.06 ± 0.49, P = 0.09, t-test).
In eyes with macular edema secondary to RVO, pars plana vitrectomy with internal limiting membrane peeling can resolve macular edema, but the improvement in BCVA was not statistically significant in this study.
评估玻璃体切除术联合内界膜剥除术治疗视网膜静脉阻塞（RVO）继发黄斑水肿的效果。
9例因视网膜中央静脉阻塞或视网膜分支静脉阻塞所致黄斑水肿而视力下降的患者接受了玻璃体切除术，术中切除视网膜前玻璃体膜，剥除经吲哚菁绿染色的内界膜，进行气液交换，并于术后采取俯卧位。术前及术后测量最佳矫正视力（BCVA）及光学相干断层扫描测量的中央凹厚度，然后进行比较以评估手术效果。
所有病例视网膜内出血和视网膜增厚在术后2个月内减轻。所有视网膜中央静脉阻塞病例及3/6视网膜分支静脉阻塞病例的视力均有改善。黄斑厚度的降低具有统计学意义（术后黄斑平均厚度361±61.1与术前黄斑平均厚度563.9±90.0相比，P = 0.001，t检验）。BCVA的改善无统计学意义（术前平均LogMAR视力1.23±0.29与术后平均LogMAR视力1.06±0.49相比，P = 0.09，t检验）。
在RVO继发黄斑水肿的眼中，玻璃体切除术联合内界膜剥除术可缓解黄斑水肿，但本研究中BCVA的改善无统计学意义。
