Department of Radiology, Breast Unit, Queen Elizabeth Hospital, Sheriff Hill, UK.
J Breast Cancer. 2011 Mar;14(1):28-32. doi: 10.4048/jbc.2011.14.1.28. Epub 2011 Mar 31.
Breast cancers can be asymptomatic at an early stage and hence screening programmes play an important role in detecting breast cancers early. Even in those patients who present with breast symptoms, breast cancers may be present at a site remote to the site of symptoms. In this study, we aimed to assess the frequency, site and imaging modality used to identify these incidental cancers in the symptomatic one-stop breast clinic.
All patients who were seen in our breast clinic with breast symptoms over a two-year period were included in the study. We correlated the presenting symptoms of patients diagnosed with breast cancer with imaging (mammogram and ultrasound) findings. Incidental cancers were defined as "histologically confirmed breast cancers which were impalpable, remote to the site of symptoms and only identified on imaging."
In the study period, 281 women were diagnosed with breast cancer out of 4,400 patients seen at the one-stop breast clinic. Thirty six patients (12.8%) diagnosed with breast cancer had an incidental cancer which was only identified by imaging. The majority of contralateral, incidental cancers were identified by both mammography and ultrasound (US) and patients were all above 35 years.
We suggest mammography of both breasts and US of the symptomatic breast in order to identify incidental cancers.
早期乳腺癌可能无症状，因此筛查计划在早期发现乳腺癌方面发挥着重要作用。即使在出现乳房症状的患者中，乳腺癌也可能发生在远离症状部位的部位。在这项研究中，我们旨在评估在症状性一站式乳房诊所中识别这些偶发性癌症的频率、部位和影像学方式。
在两年的时间里，所有在我们的乳房诊所就诊的有乳房症状的患者均被纳入研究。我们将诊断为乳腺癌的患者的症状与影像学（乳房 X 线摄影和超声）发现相关联。偶发性癌症被定义为“组织学证实的乳腺癌，触诊不可触及，远离症状部位，仅通过影像学发现”。
在研究期间，在一站式乳房诊所就诊的 4400 名患者中，有 281 名被诊断为乳腺癌。36 名（12.8%）被诊断为乳腺癌的患者患有偶发性癌症，仅通过影像学发现。大多数对侧偶发性癌症通过乳房 X 线摄影和超声（US）均能识别，且患者均超过 35 岁。
我们建议对双侧乳房进行乳房 X 线摄影和对有症状的乳房进行 US，以识别偶发性癌症。
