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在快速诊断乳腺门诊就诊的有症状女性中进行的乳腺钼靶检查:一项前瞻性研究。

Mammography in symptomatic women attending a rapid diagnosis breast clinic: a prospective study.

作者信息

Biggs M J P, Ravichandran D

机构信息

Breast Unit, Luton & Dunstable Hospital, Luton, Bedfordshire, UK.

出版信息

Ann R Coll Surg Engl. 2006 May;88(3):306-8. doi: 10.1308/003588406X98603.

Abstract

INTRODUCTION

We determined whether it is safe to avoid mammograms in a group of symptomatic women with a non-suspicious history and clinical examination.

PATIENTS AND METHODS

Symptomatic women aged 35 years or over newly referred to a rapid-diagnosis breast clinic underwent mammography on arrival in the clinic. A breast radiologist reported on the mammograms. An experienced clinician who was unaware of the mammogram findings examined patients and decided whether a mammogram was indicated or not. If not, a management plan was formulated. Mammogram findings were then provided to the clinician and any change to the original management plan as a result of mammography was recorded.

RESULTS

In two-thirds (67%) of 218 patients, the clinician felt a mammogram was indicated. Half (46%) of these mammograms showed an abnormality; of these abnormal mammograms, 41% were breast cancer. Among the third (n = 71) of mammograms felt not to be indicated, 3 showed abnormalities of which 2 were breast cancer. One cancer was not suspected clinically or mammographically but was diagnosed on cyto/histopathological assessment.

CONCLUSIONS

A significant proportion of patients attending a symptomatic breast clinic have a non-suspicious history and normal clinical findings on examination. However, even in this group avoiding mammograms risks missing clinically occult breast cancers. It would appear sensible to offer mammograms to all symptomatic women over 35 years of age.

摘要

引言

我们确定了对于一组有非可疑病史且临床检查无异常的有症状女性,不进行乳房X光检查是否安全。

患者与方法

新转诊至快速诊断乳腺门诊的35岁及以上有症状女性在抵达门诊时接受乳房X光检查。一名乳腺放射科医生对乳房X光片进行报告。一名不了解乳房X光检查结果的经验丰富的临床医生对患者进行检查,并决定是否需要进行乳房X光检查。如果不需要,则制定管理计划。然后将乳房X光检查结果提供给临床医生,并记录因乳房X光检查而对原始管理计划做出的任何更改。

结果

在218例患者中,三分之二(67%)的临床医生认为需要进行乳房X光检查。这些乳房X光检查中有一半(46%)显示异常;在这些异常乳房X光检查中,41%为乳腺癌。在三分之一(n = 71)被认为不需要进行的乳房X光检查中,有3例显示异常,其中2例为乳腺癌。有1例癌症在临床或乳房X光检查中均未被怀疑,但在细胞/组织病理学评估中被诊断出来。

结论

相当一部分到有症状乳腺门诊就诊的患者有非可疑病史且检查时临床结果正常。然而,即使在这组患者中,不进行乳房X光检查也有漏诊临床隐匿性乳腺癌的风险。对所有35岁以上有症状的女性进行乳房X光检查似乎是明智的。

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