Department of Surgery, Yeungnam University College of Medicine, Daegu, Korea.
J Breast Cancer. 2011 Mar;14(1):69-71. doi: 10.4048/jbc.2011.14.1.69. Epub 2011 Mar 31.
The common sites of metastasis of breast cancer are bone, lung, and liver, but gastrointestinal metastasis from breast cancer is rare. We experienced a case of solitary ileal metastasis from breast cancer. A 45-years-old woman presented with melena for several weeks. She showed no other abdominal symptoms. Colonoscopy findings showed an ulcerative mucosal lesion in the terminal ileum, and biopsy was performed. Pathologic examination revealed metastatic carcinoma, originated from breast. The tumor cells were positive for estrogen receptor and negative for Cdx-2. She had had a previous medical history of bilateral breast cancer and undergone breast conserving surgery with sentinel lymph node biopsy for both breasts. The torso positron emission tomography scan at 19 months after surgery showed mildly increased uptake in the terminal ileum which was considered as inflammation. Finally, she was diagnosed with solitary ileal metastasis from breast cancer at 22 months after surgery.
乳腺癌常见的转移部位是骨、肺和肝,但胃肠道转移较为罕见。我们遇到了一例乳腺癌单发回肠转移。一名 45 岁女性因黑便数周就诊。她没有其他腹部症状。结肠镜检查发现末端回肠有溃疡性黏膜病变,并进行了活检。病理检查显示转移性癌,来源于乳腺。肿瘤细胞雌激素受体阳性,Cdx-2 阴性。她之前有双侧乳腺癌病史,并接受了保乳手术和双侧前哨淋巴结活检。手术 19 个月后的胸腹部正电子发射断层扫描显示末端回肠有轻度摄取增加,考虑为炎症。最终,手术 22 个月后诊断为乳腺癌单发回肠转移。