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三阴性乳腺浸润性小叶癌表现为小肠梗阻。

Triple negative invasive lobular carcinoma of the breast presents as small bowel obstruction.

作者信息

Khokhlova Mariya, Roppelt Heidi, Gluck Bradley, Liu Jingxuan, Haye Kester, Pak Sang, Kapenhas Edna

机构信息

Department of Internal Medicine, Stony Brook Medicine at Southampton Hospital, 240 Meeting House Lane, Southampton, NY, 11968, United States.

Director of Internal Medicine Residency Program, Department of Internal Medicine, Stony Brook at Southampton Hospital, 240 Meeting House Lane, Southampton, NY, 11968, United States.

出版信息

Int J Surg Case Rep. 2017;37:79-82. doi: 10.1016/j.ijscr.2017.06.002. Epub 2017 Jun 8.

DOI:10.1016/j.ijscr.2017.06.002
PMID:28648876
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5480825/
Abstract

Metastasis from breast carcinoma to the gastrointestinal tract (GIT) is very uncommon. To date, only a few cases have been described worldwide. Of those which do metastasize to the GIT, only estrogen receptor (ER), progesterone receptor (PR) and HER2-neu receptor positive cancers have been reported and none have been mentioned in the U.S. We report a case of a 70-year-old white female with history of triple negative lobular carcinoma eight years earlier who presented with solitary jejunal mass causing obstruction.

摘要

乳腺癌转移至胃肠道（GIT）极为罕见。迄今为止，全球仅报道过少数病例。在那些确实转移至胃肠道的病例中，仅报告过雌激素受体（ER）、孕激素受体（PR）和HER2-神经受体阳性的癌症，而美国尚未有相关病例报道。我们报告一例70岁白人女性病例，其8年前有三阴性小叶癌病史，此次因孤立性空肠肿块导致肠梗阻就诊。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7639/5480825/9a558e79edbb/gr4v5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7639/5480825/13f665697509/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7639/5480825/0b61ee392ddd/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7639/5480825/3e0565895f06/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7639/5480825/9a558e79edbb/gr4v5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7639/5480825/13f665697509/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7639/5480825/0b61ee392ddd/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7639/5480825/3e0565895f06/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7639/5480825/9a558e79edbb/gr4v5.jpg

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本文引用的文献

1
Jejunal obstruction caused by metastasis from an undiagnosed breast cancer: a case report.未确诊乳腺癌转移所致空肠梗阻：一例报告
Tumori. 2012 May-Jun;98(3):89e-91e. doi: 10.1700/1125.12419.
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Case report and literature review: Metastatic lobular carcinoma of the breast an unusual presentation.病例报告及文献综述：乳腺小叶癌转移的一种罕见表现。
Int J Surg Case Rep. 2011;2(8):301-5. doi: 10.1016/j.ijscr.2011.06.010. Epub 2011 Oct 12.
3
Solitary small bowel metastasis from breast cancer.乳腺癌单发小肠转移。
三阴性浸润性导管乳腺癌伴阴性钼靶的十二指肠转移：病例报告及文献复习。
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Hormone receptor status, tumor characteristics, and prognosis: a prospective cohort of breast cancer patients.激素受体状态、肿瘤特征与预后：乳腺癌患者的一项前瞻性队列研究
Breast Cancer Res. 2007;9(1):R6. doi: 10.1186/bcr1639.
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Metastatic breast cancer to the gastrointestinal tract: a case series and review of the literature.胃肠道转移性乳腺癌：病例系列及文献综述
World J Gastroenterol. 2006 Oct 14;12(38):6219-24. doi: 10.3748/wjg.v12.i38.6219.
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Colonic metastasis from carcinoma of the breast that mimics a primary intestinal cancer.酷似原发性肠癌的乳腺癌结肠转移。
Yonsei Med J. 2006 Aug 31;47(4):578-82. doi: 10.3349/ymj.2006.47.4.578.
7
Race, breast cancer subtypes, and survival in the Carolina Breast Cancer Study.《卡罗来纳乳腺癌研究中的种族、乳腺癌亚型与生存率》
JAMA. 2006 Jun 7;295(21):2492-502. doi: 10.1001/jama.295.21.2492.
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Distinct molecular mechanisms underlying clinically relevant subtypes of breast cancer: gene expression analyses across three different platforms.乳腺癌临床相关亚型背后不同的分子机制：跨三个不同平台的基因表达分析
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9
The distinctive nature of HER2-positive breast cancers.HER2 阳性乳腺癌的独特性质。
N Engl J Med. 2005 Oct 20;353(16):1652-4. doi: 10.1056/NEJMp058197.
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Conservation of breast cancer molecular subtypes and transcriptional patterns of tumor progression across distinct ethnic populations.不同种族人群中乳腺癌分子亚型的保守性及肿瘤进展的转录模式
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