Rowbotham M C, Lowenstein D H
Department of Neurology, University of California, San Francisco 94143.
Annu Rev Med. 1990;41:417-22. doi: 10.1146/annurev.me.41.020190.002221.
Neurologic consequences of cocaine use frequently present as medical emergencies in the form of stroke, repeated seizures, encephalopathy, acute headache, and unusual transient neurological deficits. The often fatal or disabling neurologic syndromes have only recently been recognized but are now well documented. Cocaine use is a significant cause of stroke in young adults, and the full, long-term ramifications of maternal cocaine use on the fetus will not be known for years to come. Unfortunately, there is not effective treatment other than abstinence, and our understanding of the pathophysiology of cocaine-associated neurologic illness remains limited.
使用可卡因的神经学后果常常以中风、反复癫痫发作、脑病、急性头痛和异常短暂性神经功能缺损等医疗急症的形式出现。这些往往致命或致残的神经综合征直到最近才被认识到，但现在已有充分记录。使用可卡因是年轻人中风的一个重要原因，而母亲使用可卡因对胎儿的全面、长期影响在未来几年内仍无法得知。不幸的是，除了戒除之外没有有效的治疗方法，而且我们对可卡因相关神经疾病的病理生理学的了解仍然有限。
