Rodrigues Luis Vaz, Gandara Judit, Pires João, Duarte Raquel, Calvário Fernando, Dominguez Miguel, Carvalho Aurora, Seca Rui
Centro Hospitalar de Coimbra, Pulmunology, Quinta dos Vales, S. Martinho do Bispo, Coimbra, 3041-801, Portugal.
BMJ Case Rep. 2009;2009. doi: 10.1136/bcr.05.2009.1847. Epub 2009 Aug 17.
We report on a patient diagnosed with disseminated (hepatic and pulmonary) tuberculosis in the context of immunosuppression following liver transplant. During the administration of anti-tuberculosis drugs an abrupt elevation of liver enzymes was detected leading us to suspect drug toxicity rather than graft rejection. Nevertheless, careful surveillance and adjustment of serum levels of immunosuppressant drugs permitted continuance of tuberculosis treatment with no further side effects.
我们报告了一例肝移植后免疫抑制状态下被诊断为播散性（肝脏和肺部）结核的患者。在抗结核药物治疗期间，检测到肝酶突然升高，这使我们怀疑是药物毒性而非移植排斥反应。尽管如此，通过仔细监测和调整免疫抑制药物的血清水平，得以继续进行抗结核治疗且未出现进一步的副作用。
