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移植肝孤立性结核：一例报告并文献复习

Isolated tuberculosis of transplanted liver, a case report and review of the literature.

作者信息

Geramizadeh Bita, Nikeghbalian Saman, Janghorban Parisa, Malekhosseini Seyed Ali

机构信息

Transplant Research Center, Shiraz University of Medical Science, Shiraz, IR Iran ; Department of Pathology, Shiraz University of Medical Science, Shiraz, IR Iran.

出版信息

Hepat Mon. 2013 May 21;13(5):e6691. doi: 10.5812/hepatmon.6691. Print 2013 May.

DOI:10.5812/hepatmon.6691
PMID:23914226
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3728975/
Abstract

INTRODUCTION

Recipients of liver transplantation are prone to different types of infections such as tuberculosis (TB).

CASE PRESENTATION

Herein we report a 59-year-old man with liver transplantation due to HBV cirrhosis who developed isolated hepatic TB, 18 months after OLT (orthotropic liver transplantation). He has been successfully treated with anti-TB regimen and now after 12 months he is completely symptom-free.

CONCLUSIONS

Organ transplantation and treatment of transplanted patients with immunosuppressive drugs would prone them to various unusual infections. One of these is unusual primary involvement of liver by tuberculosis which has been extremely rare in the previous reports.

摘要

引言

肝移植受者易发生不同类型的感染，如结核病（TB）。

病例报告

在此，我们报告一名59岁因乙肝肝硬化接受肝移植的男性患者，在原位肝移植（OLT）18个月后发生孤立性肝结核。他通过抗结核方案得到成功治疗，现在12个月后已完全无症状。

结论

器官移植以及用免疫抑制药物治疗移植患者会使他们易发生各种不寻常的感染。其中之一是肝脏罕见地被结核原发累及，这在既往报告中极为罕见。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7bb/3728975/a413fa762b7d/hepatmon-13-05-6691-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7bb/3728975/a413fa762b7d/hepatmon-13-05-6691-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7bb/3728975/a413fa762b7d/hepatmon-13-05-6691-g001.jpg

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本文引用的文献

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Post liver transplant tuberculosis.肝移植后结核病
BMJ Case Rep. 2009;2009. doi: 10.1136/bcr.05.2009.1847. Epub 2009 Aug 17.
2
Mycobacterium tuberculosis infection in liver transplantation.肝移植术后结核分枝杆菌感染。
Liver Transpl. 2010 Oct;16(10):1129-35. doi: 10.1002/lt.22133.
3
Mycobacterium tuberculosis in solid organ transplant recipients.实体器官移植受者中的结核分枝杆菌。
Hepat Mon. 2013 Jun 18;13(6):e9389. doi: 10.5812/hepatmon.9389. eCollection 2013.
Am J Transplant. 2009 Dec;9 Suppl 4:S57-62. doi: 10.1111/j.1600-6143.2009.02894.x.
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Tuberculosis in liver transplant recipients: a systematic review and meta-analysis of individual patient data.肝移植受者中的结核病：个体患者数据的系统评价和荟萃分析
Liver Transpl. 2009 Aug;15(8):894-906. doi: 10.1002/lt.21709.
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Clin Infect Dis. 2009 May 1;48(9):1276-84. doi: 10.1086/597590.
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CT findings in fatal primary intestinal tuberculosis in a liver transplant recipient.
Diagn Interv Radiol. 2008 Dec;14(4):221-4.
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