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2009年甲型H1N1流感所致成人呼吸窘迫综合征合并妊娠:体外膜肺氧合支持下母婴均获成功救治

Adult respiratory distress syndrome caused by 2009 H1N1 influenza during pregnancy: success of ECMO for both the mother and the child.

作者信息

Courouble Patricia, Geukens Paul, Laarbaui Fatima, Beauloye Christophe, Van Caenegem Olivier, Jacquet Luc-Marie

机构信息

Department of Cardiovascular Intensive Care Unit, Cliniques Universitaires St. Luc, Brussels, Belgium.

出版信息

J Extra Corpor Technol. 2011 Jun;43(2):75-8.

PMID:21848176
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4680027/
Abstract

Extracorporeal membrane oxygenation (ECMO) is a technique that provides support to selected patients with severe respiratory failure. During the 2009 H1N1 influenza infection outbreak, ECMO was used with a good impact on survival for pregnant women, who are at higher risk of H1N1 influenza infection. However, there is little information about the survival of fetus post-ECMO therapy in the literature. We present a case report of a pregnant patient with severe adult respiratory distress syndrome secondary to 2009 H1N1 influenza treated with ECMO. The outcome was good both for the mother and her fetus. At 1-year follow-up, her child had no neurological or clinical abnormalities. We conclude that ECMO can be used safely during pregnancy with a good neurological and clinical outcome for the fetus.

摘要

体外膜肺氧合(ECMO)是一种为选定的严重呼吸衰竭患者提供支持的技术。在2009年甲型H1N1流感感染爆发期间,ECMO被用于治疗甲型H1N1流感感染风险较高的孕妇,对其生存产生了良好影响。然而,文献中关于ECMO治疗后胎儿存活情况的信息很少。我们报告一例因2009年甲型H1N1流感继发严重成人呼吸窘迫综合征的孕妇接受ECMO治疗的病例。母亲和胎儿的结局均良好。在1年的随访中,她的孩子没有神经或临床异常。我们得出结论,孕期可安全使用ECMO,胎儿的神经和临床结局良好。

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本文引用的文献

1
Severe 2009 H1N1 influenza in pregnant and postpartum women in California.加利福尼亚州孕妇和产后妇女中的严重 2009 H1N1 流感。
N Engl J Med. 2010 Jan 7;362(1):27-35. doi: 10.1056/NEJMoa0910444. Epub 2009 Dec 23.
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Extracorporeal Membrane Oxygenation for 2009 Influenza A(H1N1) Acute Respiratory Distress Syndrome.体外膜肺氧合治疗2009年甲型H1N1流感所致急性呼吸窘迫综合征
JAMA. 2009 Nov 4;302(17):1888-95. doi: 10.1001/jama.2009.1535. Epub 2009 Oct 12.
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Extracorporeal membrane oxygenation in pregnancy.
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Acute respiratory distress syndrome in pregnancy.妊娠期急性呼吸窘迫综合征
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Cardiopulmonary complications of pregnancy.妊娠的心肺并发症
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