Tang Zhen, Zhou Ying, Li Ming-Xia
Division of Neonatology, First Affiliated Hospital of Xinjiang Medical University, Urumqi, China.
Zhongguo Dang Dai Er Ke Za Zhi. 2011 Aug;13(8):627-30.
To study the clinical features of feeding intolerance in preterm infants in order to provide clinical evidence for preventing feeding intolerance.
A total of 716 preterm infants hospitalized in the First Affiliated Hospital of Xinjiang Medical University between January 2007 and December 2009 were enrolled. The clinical data of the infants were retrospectively studied.
Feeding intolerance occurred in 197 (27.5%) out of 716 infants, with an incidence of 76.4% in the very low birth weight infants. Simple gastric retention (47.2%) was found as the most common clinical manifestation. Feeding intolerance usually occurred within 3 days after feeding. Compared with the preterm infants with feeding success, the preterm infants with feeding intolerance showed lower gestational age and birth weight, more delayed feeding and higher rate of asphyxia and respiratory diseases (P<0.05). There were no significant differences in the gender, maternal age, ethnic group, delivery way and the incidence of fetal distress between the two groups. With increasing gestational age, increasing birth weight, early feeding, the incidence of feeding intolerance in preterm infants was reduced.
The low gestational age, low birth weight, delayed feeding and complications may be associated with the development of feeding intolerance in preterm infants.
研究早产儿喂养不耐受的临床特征，为预防喂养不耐受提供临床依据。
选取2007年1月至2009年12月在新疆医科大学第一附属医院住院的716例早产儿，对其临床资料进行回顾性研究。
716例早产儿中197例（27.5%）发生喂养不耐受，极低出生体重儿发生率为76.4%。最常见的临床表现为单纯胃潴留（47.2%）。喂养不耐受通常在喂养后3天内发生。与喂养成功的早产儿相比，喂养不耐受的早产儿胎龄和出生体重更低，喂养开始时间更晚，窒息和呼吸系统疾病发生率更高（P<0.05）。两组在性别、产妇年龄、民族、分娩方式及胎儿窘迫发生率方面无显著差异。随着胎龄增加、出生体重增加、早期喂养，早产儿喂养不耐受的发生率降低。
胎龄小、出生体重低、喂养延迟及并发症可能与早产儿喂养不耐受的发生有关。
