Gajović Olgica, Tomović Miroslav, Stanarcić Jelena, Canović Predrag, Todorović Zoran, Lazić Zorica
Department for Infectious Diseases, Clinical Center of Kragujevac, Kragujevac, Serbia.
Med Glas (Zenica). 2011 Aug;8(2):277-9.
A retrospective study was performed to evaluate the clinical characteristics of nosocomial infections in patients with acute infection of central nervous system (ACNS infections). The study included 1,686 patients admitted to the ICU. Of 1,686 patients, 936 (55.5%) had ACNS infection. Nosocomial infections was confirmed in 221 (23.6%) patients with ACNS infection. The most common risk factors for ICU-acquired nosocomial infections were consciousness disorder, mechanical ventilation and nasogastric tube. The coagulase - negative Staphylococcus aureus was the most frequent isolated pathogen (285 isolates, 56.5%). Results suggest that a persistently high level of therapeutic activity and persistently depressed consciousness after the ICU admission are associated with the occurrence of hospital-acquired infection in critically ill patients hospitalized at a medical ICU.
进行了一项回顾性研究，以评估中枢神经系统急性感染（ACNS感染）患者医院感染的临床特征。该研究纳入了1686例入住重症监护病房（ICU）的患者。在这1686例患者中，936例（55.5%）患有ACNS感染。221例（23.6%）ACNS感染患者确诊发生医院感染。ICU获得性医院感染最常见的危险因素是意识障碍、机械通气和鼻胃管。凝固酶阴性金黄色葡萄球菌是最常分离出的病原体（285株，56.5%）。结果表明，入住ICU后持续高水平的治疗活动和持续意识障碍与入住医疗ICU的重症患者发生医院获得性感染有关。
