Biernat-Sudolska Małgorzata, Rojek-Zakrzewska Danuta, Rzepecka-Weglarz Beata, Kosz-Vnenchak Magdalena
Zakład Wirusologii Katedra Mikrobiologii UJ, Collegium Medicum Kraków, Polska.
Ginekol Pol. 2011 May;82(5):359-62.
Pregnancy promotes ureaplasma vaginal colonization. This creates the possibility of vertical transmission of these organisms to the child. These microorganisms can cause complications during pregnancy and poor condition of newborn.
Objectives of this study were to analyze the vertical transmission of different species of ureaplasmas in term newborns without respiratory distress.
The study included 50 mothers and 50 of their newborn children. Swabs were obtained from swabs of the cervix in women and tracheal aspirates from neonates. The presence of ureaplasmas was confirmed by culture and PCR. Ureaplasmas species identification was performed using PCR.
infection of ureaplasmas was found in 21 women (42%). Predominant species was U. parvum, which was found in 18 women. In 3 patients only the presence of U. urealyticum was confirmed. Ureaplasma infection in mother and her newborn baby was confirmed in 8 (17.4%) mother-child pairs, including 6 of these cases showing the presence of U. parvum and 2 U. urealyticum. The incidence of vertical transmission of ureaplasma infection was assessed at 33% for U. parvum and 67% for U. urealyticum, and the total for both species at 38%. It should be noted that in the group of 18 women infected with U.parvum, in 12 cases there was no transmission of infection to the child. However in 3 women infected with U. urealyticum 2 cases of transmission from mother to child were observed (67%). Although the group infected with U. urealyticum accounted for only 3 women, our preliminary observations may suggest that this species is probably more likely to be transferred from mother to child.
Infection with U. urealyticum may be more frequently transferred from the genital tract of mother to child.
妊娠会促进脲原体在阴道的定植。这使得这些微生物有垂直传播给胎儿的可能性。这些微生物可在孕期引发并发症并导致新生儿状况不佳。
本研究的目的是分析足月无呼吸窘迫新生儿中不同种类脲原体的垂直传播情况。
该研究纳入了50名母亲及其50名新生儿。从女性宫颈拭子和新生儿气管吸出物中获取样本。通过培养和聚合酶链反应(PCR)确认脲原体的存在。使用PCR进行脲原体种类鉴定。
在21名女性(42%)中发现了脲原体感染。优势菌种是微小脲原体,在18名女性中被发现。在3名患者中仅确认存在解脲脲原体。在8对母婴(17.4%)中确认了母亲及其新生儿的脲原体感染,其中6例显示存在微小脲原体,2例存在解脲脲原体。微小脲原体感染的垂直传播发生率评估为33%,解脲脲原体为67%,两种菌种的总发生率为38%。应当指出的是,在18名感染微小脲原体的女性组中,有12例感染未传播给孩子。然而,在3名感染解脲脲原体的女性中,观察到2例母婴传播(67%)。尽管感染解脲脲原体的组仅占3名女性,但我们的初步观察可能表明该菌种更有可能从母亲传播给孩子。
解脲脲原体感染可能更频繁地从母亲生殖道传播给孩子。