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家畜肾脏系统综述及肾脏活动的昼夜变化。

A review of the renal system and diurnal variations of renal activity in livestock.

机构信息

Department of Physiology, Faculty of Life Sciences, University of Szczecin, Al, Piastow 40 B, 71-065 Szczecin, Poland.

出版信息

Ir Vet J. 2007 Mar 1;60(3):161-8. doi: 10.1186/2046-0481-60-3-161.

Abstract

Kidneys are the main organs regulating water-electrolyte homeostasis in the body. They are responsible for maintaining the total volume of water and its distribution in particular water spaces, for electrolyte composition of systemic fluids and also for maintaining acid-base balance. These functions are performed by the plasma filtration process in renal glomeruli and the processes of active absorption and secretion in renal tubules, all adjusted to an 'activity-rest' rhythm. These diurnal changes are influenced by a 24-hour cycle of activity of hormones engaged in the regulation of renal activity. Studies on spontaneous rhythms of renal activity have been carried out mainly on humans and laboratory animals, but few studies have been carried out on livestock animals. Moreover, those results cover only some aspects of renal physiology. This review gives an overview of current knowledge concerning renal function and diurnal variations of some renal activity parameters in livestock, providing greater understanding of general chronobiological processes in mammals. Detailed knowledge of these rhythms is useful for clinical, practical and pharmacological purposes, as well as studies on their physical performance.

摘要

肾脏是调节体内水-电解质平衡的主要器官。它们负责维持总水量及其在特定水空间的分布,维持全身液体的电解质组成,也负责维持酸碱平衡。这些功能是通过肾小体中的血浆过滤过程以及肾单位中的主动吸收和分泌过程来实现的,所有这些过程都被调整到“活动-休息”的节奏中。这些昼夜变化受到参与调节肾脏活动的激素 24 小时活动周期的影响。对肾脏活动自发节律的研究主要在人类和实验动物中进行,但对家畜的研究较少。此外,这些结果仅涵盖了肾脏生理学的一些方面。本文综述了关于家畜肾脏功能和一些肾脏活动参数昼夜变化的最新知识,为哺乳动物的一般生物钟过程提供了更深入的了解。详细了解这些节律对临床、实际和药理学目的以及对其体力活动的研究都很有用。

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