首次通过聚合酶链反应和标准方法同时研究淋病奈瑟菌和沙眼衣原体感染的患病率。
The first simultaneous study of the prevalence of Neisseria gonorrhoeae and Chlamydia trachomatis infections by polymerase chain reaction and standard methods.
作者信息
Ouzounova-Raykova Vessela V, El Tibi Mohamed, Mitov Ivan G
出版信息
Sex Health. 2011 Sep;8(3):442-4. doi: 10.1071/SH11056.
BACKGROUND
Neisseria gonorrhoeae and Chlamydia trachomatis are important sexually transmissible pathogens. The aim of the present study was to determine their prevalence in symptomatic and asymptomatic people.
METHODS
Polymerase chain reaction (PCR) and standard methods were tested for 413 specimens.
RESULTS
The registered prevalence with PCR was N. gonorrhoeae 2.66% and C. trachomatis 0.73%. One man showed co-infection. Standard methods demonstrated lower sensitivity in finding N. gonorrhoeae and C. trachomatis in comparison with the PCR.
CONCLUSIONS
This is the first simultaneous study in Bulgaria for detection of N. gonorrhoeae and C. trachomatis by PCR and standard methods. N. gonorrhoeae was found to be a more frequent infection. Further investigations are needed.
背景
淋病奈瑟菌和沙眼衣原体是重要的性传播病原体。本研究的目的是确定它们在有症状和无症状人群中的流行率。
方法
对413份标本进行了聚合酶链反应（PCR）和标准方法检测。
结果
PCR检测出的淋病奈瑟菌流行率为2.66%，沙眼衣原体为0.73%。一名男性显示为合并感染。与PCR相比，标准方法在检测淋病奈瑟菌和沙眼衣原体时敏感性较低。
结论
这是保加利亚首次同时采用PCR和标准方法检测淋病奈瑟菌和沙眼衣原体的研究。发现淋病奈瑟菌感染更为常见。需要进一步调查。
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