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土耳其有症状、无症状和不孕妇女的宫颈拭子标本中沙眼衣原体和淋病奈瑟菌的流行情况。

The prevalence of Chlamydia trachomatis and Neisseria gonorrhoeae in the endocervical swab specimens of symptomatic, asymptomatic and infertile women in Turkey.

机构信息

Department of Medical Microbiology, Gaziantep University, Faculty of Medicine, Universite Bulvari, Gaziantep 27310, Turkey.

出版信息

Arch Gynecol Obstet. 2011 Jun;283(6):1349-55. doi: 10.1007/s00404-010-1694-8. Epub 2010 Sep 25.

Abstract

PURPOSE

To investigate C. trachomatis and N. gonorrhoeae prevalence in three different female populations in Turkey.

METHODS

A total of 370 women, 170 symptomatic, 100 asymptomatic, and 100 infertile, were included. Of the endocervical specimens collected from all women using a Dacron swab, the first one was taken to Stuart's transport medium to culture, while the second one was transferred onto slides to perform direct fluorescent antibody test (DFA) and Gram staining, and the third specimen was used for Becton Dickinson BDProbeTec ET system (BDPT).

RESULTS

C. trachomatis was detected in 5.16% of symptomatic, 1.11% of asymptomatic, and 2.15% of infertile women with BDPT. Sensitivity and specificity of the DFA test were 72.73 and 97.85%, respectively. N. gonorrhoeae was detected in 2.42% of symptomatic and in 1.02% of infertile women. N. gonorrhoeae was not detected in any asymptomatic women. In N. gonorrhoeae-positive patients, sensitivity and specificity of culture were 60 and 100%, respectively, while they were 80 and 100% for BDPT.

CONCLUSIONS

Prevalence of N. gonorrhoeae and C. trachomatis was detected to be low in Turkish women, and the difference between the groups was not significant. Both agents were more prevalent in subjects over 25 years of age.

摘要

目的

在土耳其的三个不同女性人群中调查沙眼衣原体和淋病奈瑟菌的流行情况。

方法

共纳入 370 名女性,170 名有症状,100 名无症状,100 名不孕。使用 Dacron 拭子从所有女性的宫颈标本中采集的第一个标本被送往 Stuart 的运输培养基进行培养,而第二个标本被转移到载玻片上进行直接荧光抗体试验(DFA)和革兰氏染色,第三个标本用于 Becton Dickinson BDProbeTec ET 系统(BDPT)。

结果

BDPT 检测到 5.16%的有症状、1.11%的无症状和 2.15%的不孕女性存在沙眼衣原体。DFA 试验的敏感性和特异性分别为 72.73%和 97.85%。淋病奈瑟菌在 2.42%的有症状和 1.02%的不孕女性中被检测到。在任何无症状女性中均未检测到淋病奈瑟菌。在淋病奈瑟菌阳性患者中,培养的敏感性和特异性分别为 60%和 100%,而 BDPT 的敏感性和特异性分别为 80%和 100%。

结论

在土耳其女性中,淋病奈瑟菌和沙眼衣原体的流行率较低,且各组之间无显著差异。这两种病原体在 25 岁以上的人群中更为常见。

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